Chronic heart failure reduces Akt phosphorylation in human skeletal muscle: relationship to muscle size and function (Q34785071)

4 August 2017

Chronic heart failure reduces Akt phosphorylation in human skeletal muscle: relationship to muscle size and function (English)

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4 August 2017

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chronic heart failure

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Michael J Toth

1

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4 August 2017

Kimberly Ward

2

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4 August 2017

Jos van der Velden

3

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4 August 2017

Mark S Miller

4

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4 August 2017

Peter Vanburen

5

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4 August 2017

Martin M Lewinter

6

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4 August 2017

Philip A Ades

7

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4 August 2017

language of work or name

English

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publication date

30 December 2010

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Journal of Applied Physiology

4 August 2017

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4 August 2017

110

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4 August 2017

4

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4 August 2017

892-900

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Mechanisms underlying skeletal muscle weakness in human heart failure: alterations in single fiber myosin protein content and function

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Inducible activation of Akt increases skeletal muscle mass and force without satellite cell activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Reduced knee extensor function in heart failure is not explained by inactivity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

AMPK phosphorylation of raptor mediates a metabolic checkpoint

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

AKT/PKB signaling: navigating downstream

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Protein kinase B/Akt: a nexus of growth factor and cytokine signaling in determining muscle mass

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Human skeletal muscle atrophy in amyotrophic lateral sclerosis reveals a reduction in Akt and an increase in atrogin-1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Molecular determinants of skeletal muscle mass: getting the "AKT" together

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Transgenic overexpression of locally acting insulin-like growth factor-1 inhibits ubiquitin-mediated muscle atrophy in chronic left-ventricular dysfunction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

The relationship between leg power and physical performance in mobility-limited older people

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Reduction of insulin-like growth factor-I expression in the skeletal muscle of noncachectic patients with chronic heart failure.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Insulin-like growth factor I in skeletal muscle after weight-lifting exercise in frail elders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Deficient insulin-like growth factor I in chronic heart failure predicts altered body composition, anabolic deficiency, cytokine and neurohormonal activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Skeletal muscle abnormalities and evidence for their role in symptom generation in chronic heart failure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Insulin resistance in chronic heart failure: relation to severity and etiology of heart failure.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Mechanism of activation of protein kinase B by insulin and IGF-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Examination of data normalization procedures for expressing peak VO2 data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Cardiac disability. The impact of coronary heart disease on patients' daily activities.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Resistance training increases total daily energy expenditure in disabled older women with coronary heart disease.

7 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Resistance training on physical performance in disabled older female cardiac patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Beneficial effects of GH/IGF-1 on skeletal muscle atrophy and function in experimental heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

The effect of ageing and immobilization on structure and function of human skeletal muscle fibres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

The effect of recombinant human growth hormone and resistance training on IGF-I mRNA expression in the muscles of elderly men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Reversal of catabolism by beta-blockade after severe burns

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Insulin signalling and resistance in patients with chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Atrogin-1, MuRF1, and FoXO, as well as phosphorylated GSK-3beta and 4E-BP1 are reduced in skeletal muscle of chronic spinal cord-injured patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Functionally relevant thresholds of quadriceps femoris strength.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Skeletal muscle myofibrillar mRNA expression in heart failure: relationship to local and circulating hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Skeletal muscle myofibrillar protein metabolism in heart failure: relationship to immune activation and functional capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJAPPLPHYSIOL.00545.2010

Muscle fiber type specificity in insulin signal transduction

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075129

Maximum specific force depends on myosin heavy chain content in rat diaphragm muscle fibers

9 December 2018

1 reference

12 December 2020

Muscular levels of proinflammatory cytokines correlate with a reduced expression of insulinlike growth factor-I in chronic heart failure

1 reference

12 December 2020

Relation of the renin-angiotensin-aldosterone system to clinical state in congestive heart failure

1 reference

12 December 2020

Quantitative determination of myosin and actin in rabbit skeletal muscle

1 reference

12 December 2020

Appendicular skeletal muscle mass: measurement by dual-photon absorptiometry

1 reference

12 December 2020

The Framingham Disability Study: relationship of various coronary heart disease manifestations to disability in older persons living in the community

1 reference

12 December 2020

Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure

1 reference

12 December 2020

Daily energy expenditure in free-living heart failure patients

1 reference

12 December 2020

Effects of congestive heart failure on Ca2+ handling in skeletal muscle during fatigue

1 reference

12 December 2020

Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy

1 reference

12 December 2020

Diaphragm single-fiber weakness and loss of myosin in congestive heart failure rats

1 reference

12 December 2020

Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation

1 reference

12 December 2020

Chronic heart failure decreases cross-bridge kinetics in single skeletal muscle fibres from humans

1 reference

12 December 2020

10.1152/JAPPLPHYSIOL.00545.2010

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DOI

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4 August 2017

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4 August 2017

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