Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging. (Q34790173)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Ignacio Varela

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Claire L Navarro

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Juan Cadiñanos

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Nicolas Levy

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Jose M Freije

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

3

Alejandro P Ugalde

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

8

Fernando G Osorio

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

6

Pierre Cau

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Sandrine Pereira

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

María F Suárez

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Nicolas Foray

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Juan Cobo

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Félix de Carlos

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

0 references

publication date

29 June 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

767-772

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18587406%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nm1786

9 January 2020

exact match

0 references

cites work

Molecular bases of progeroid syndromes.

1 reference

7 January 2021

Lamin A-dependent nuclear defects in human aging

1 reference

7 January 2021

Prelamin A farnesylation and progeroid syndromes

1 reference

7 January 2021

What can progeroid syndromes tell us about human aging?

1 reference

7 January 2021

Hutchinson-Gilford progeria syndrome: review of the phenotype.

1 reference

7 January 2021

Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.

1 reference

7 January 2021

Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions

1 reference

7 January 2021

Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

1 reference

7 January 2021

Genomic instability in laminopathy-based premature aging

1 reference

7 January 2021

DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A.

1 reference

7 January 2021

Nuclear envelope defects cause stem cell dysfunction in premature-aging mice

1 reference

7 January 2021

From immature lamin to premature aging: molecular pathways and therapeutic opportunities.

1 reference

7 January 2021

Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes

1 reference

7 January 2021

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

1 reference

7 January 2021

Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome

1 reference

7 January 2021

Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition

1 reference

7 January 2021

A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.

1 reference

7 January 2021

A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation.

1 reference

7 January 2021

K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

1 reference

7 January 2021

Farnesylated lamins, progeroid syndromes and farnesyl transferase inhibitors

1 reference

7 January 2021

Multilevel modulation of the mevalonate and protein-prenylation circuitries as a novel strategy for anticancer therapy

1 reference

7 January 2021

An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.

1 reference

7 January 2021

Effects of pravastatin in murine collagen-induced arthritis

1 reference

7 January 2021

Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy

1 reference

7 January 2021

Statins and cancer prevention

1 reference

7 January 2021

Statin therapy and autoimmune disease: from protein prenylation to immunomodulation

1 reference

7 January 2021

Molecular mechanisms of action of bisphosphonates: current status.

1 reference

7 January 2021

Synergistic antimyeloma effects of zoledronate and simvastatin

1 reference

7 January 2021

Nuclei from rat liver: isolation method that combines purity with high yield.

1 reference

7 January 2021