A small number of residues in the class II molecule I-Au confer the ability to bind the myelin basic protein peptide Ac1-11 (Q34798966)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9874795%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

A small number of residues in the class II molecule I-Au confer the ability to bind the myelin basic protein peptide Ac1-11 (English)

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8 December 2019

4

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8 December 2019

author name string

C I Pearson

1

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8 December 2019

A M Gautam

2

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8 December 2019

I C Rulifson

3

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8 December 2019

H O McDevitt

5

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8 December 2019

language of work or name

English

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publication date

1 January 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9874795%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

8 December 2019

published in

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8 December 2019

volume

96

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8 December 2019

issue

1

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8 December 2019

page(s)

197-202

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Differential tolerance is induced in T cells recognizing distinct epitopes of myelin basic protein

8 December 2019

cites work

1 reference

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Evidence that the autoimmune antigen myelin basic protein (MBP) Ac1-9 binds towards one end of the major histocompatibility complex (MHC) cleft

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Crystal structure of I-Ak in complex with a dominant epitope of lysozyme

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

A peptide-binding motif for I-A(g7), the class II major histocompatibility complex (MHC) molecule of NOD and Biozzi AB/H mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Quantitative analysis of peptides from myelin basic protein binding to the MHC class II protein, I-Au, which confers susceptibility to experimental allergic encephalomyelitis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Structures of an MHC class II molecule with covalently bound single peptides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Position 71 in the alpha helix of the DR beta domain is predicted to influence peptide binding and plays a central role in allorecognition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Comparison of peptides bound to spleen and thymus class II.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

MHCPEP: a database of MHC-binding peptides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Self-peptides bound to the type I diabetes associated class II MHC molecules HLA-DQ1 and HLA-DQ8.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Selective binding of self peptides to disease-associated major histocompatibility complex (MHC) molecules: a mechanism for MHC-linked susceptibility to human autoimmune diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

The set of naturally processed peptides displayed by DR molecules is tuned by polymorphism of residue 86.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Myelin basic protein peptide complexes with the class II MHC molecules I-Au and I-Ak form and dissociate rapidly at neutral pH.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Definition of a DQ3.1-specific binding motif.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Two distinct mechanisms account for the immune response (Ir) gene control of the T cell response to pigeon cytochrome c.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

The T lymphocyte in experimental allergic encephalomyelitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

The molecular basis of class II MHC allelic control of T cell responses.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Inhibition of experimental autoimmune encephalomyelitis by a nonimmunogenic non-self peptide that binds to I-Au

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Cross-reactive antigen recognition by an encephalitogenic T cell receptor. Implications for T cell biology and autoimmunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Immunological aspects of demyelinating diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Properties of Monoclonal Antibodies to Mouse Ig Allotypes, H-2, and Ia Antigens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.197

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.197

Functional expression of a transfected murine class II MHC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.197

The DY sub-region of the sheep MHC contains an A/B gene pair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.197

HLA-DQ polymorphisms are highly selective for peptide binding interactions

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15116

Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein

26 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.197

Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.197

A hole in the T cell repertoire specific for a pigeon cytochrome c related peptide associated with amino acid substitutions on I-Ab molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.197

High affinity for class II molecules as a necessary but not sufficient characteristic of encephalitogenic determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.197

A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-Ak

21 January 2018

1 reference

12 December 2020

A novel approach to the generation of high affinity class II-binding peptides

1 reference

12 December 2020

Effect of natural polymorphism at residue 86 of the HLA-DR beta chain on peptide binding

1 reference

12 December 2020

Effect of pH on MHC class II-peptide interactions

1 reference

12 December 2020

Complex regulation of class II gene expression: analysis with class II mutant cell lines

1 reference

12 December 2020

Characterization of cell lines expressing mutant I-Ab and I-Ak molecules allows the definition of distinct serologic epitopes on A alpha and A beta polypeptides

1 reference

12 December 2020

Reversal of acute experimental autoimmune encephalomyelitis and prevention of relapses by treatment with a myelin basic protein peptide analogue modified to form long-lived peptide-MHC complexes

1 reference

12 December 2020

Differential effect of polymorphism at HLA-DR1 beta-chain positions 85 and 86 on binding and recognition of DR1-restricted antigenic peptides

1 reference

12 December 2020

Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.96.1.197

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9874795%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9874795%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PubMed publication ID

9874795

1 reference