Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability (Q34818356)

4 August 2017

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title

Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability (English)

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4 August 2017

Stefan Duensing

1

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4 August 2017

Karl Münger

series ordinal

2

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4 August 2017

language of work or name

English

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publication date

1 September 2002

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4 August 2017

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4 August 2017

21

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4 August 2017

6241-6248

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4 August 2017

40

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205709

4 August 2017

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The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

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The mouse Mps1p-like kinase regulates centrosome duplication

21 January 2018

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Establishment of the human papillomavirus type 16 (HPV-16) life cycle in an immortalized human foreskin keratinocyte cell line

21 January 2018

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Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein

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Induction of chromosome abnormalities in mouse and human epidermal keratinocytes by the human papillomavirus type 16 E7 oncogene

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Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts

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Genetic instability in epithelial tissues at risk for cancer

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A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

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Progression of human papillomavirus type 18-immortalized human keratinocytes to a malignant phenotype

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The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.

21 January 2018

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Regulation of the Cdc25A gene by the human papillomavirus Type 16 E7 oncogene

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Telomerase activation by the E6 gene product of human papillomavirus type 16.

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Cyclin-dependent kinase control of centrosome duplication

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Genetic instabilities in human cancers

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Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

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Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells

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Human papillomavirus type 16 alters human epithelial cell differentiation in vitro

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Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

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Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.

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Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation

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The role of human papillomaviruses in human cancers

21 January 2018

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Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

21 January 2018

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ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

21 January 2018

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Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

21 January 2018

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The mitotic machinery as a source of genetic instability in cancer

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Oncogenic human papillomaviruses and ploidy in cervical lesions

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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Specific chromosomal imbalances in human papillomavirus-transfected cells during progression toward immortality

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Proliferation and DNA aneuploidy in mild dysplasia imply early steps of cervical carcinogenesis

21 January 2018

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Normal human chromosome 2 induces cellular senescence in the human cervical carcinoma cell line SiHa

21 January 2018

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Surfing the p53 network

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Association of human papillomavirus types 16 and 18 E6 proteins with p53.

21 January 2018

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Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins.

21 January 2018

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21 January 2018

Viruses in human cancers

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DNA ploidy profiles as prognostic indicators in CIN lesions

21 January 2018

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7 January 2021

Human Papillomavirus Type 16 and Early Cervical Neoplasia

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7 January 2021

Centrosome abnormalities, genomic instability and carcinogenic progression

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7 January 2021

Definition of precursors

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7 January 2021

DNA aneuploidy and infection of human papillomavirus type 16 in preneoplastic lesions of the uterine cervix: correlation with progression to malignancy

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7 January 2021

Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa

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7 January 2021

Disruption of the G1/S transition in human papillomavirus type 16 E7-expressing human cells is associated with altered regulation of cyclin E

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7 January 2021

Genital warts and cervical cancer. III. Subclinical papillomaviral infection and cervical neoplasia are linked by a spectrum of continuous morphologic and biologic change

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7 January 2021

Human papillomavirus infection, centrosome aberration, and genetic stability in cervical lesions

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7 January 2021

Papillomavirus infections--a major cause of human cancers

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205709

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Dimensions Publication ID

4 August 2017

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