Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression (Q34831211)

4 August 2017

title

Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression (English)

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4 August 2017

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6

Timothy Mitchison

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4 August 2017

Natarajan Venkatesh

1

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4 August 2017

Yan Feng

2

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4 August 2017

Brian DeDecker

3

1 reference

4 August 2017

Patrick Yacono

4

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4 August 2017

David Golan

5

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4 August 2017

Frank McKeon

7

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4 August 2017

language of work or name

English

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publication date

7 June 2004

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Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

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4 August 2017

volume

101

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4 August 2017

issue

24

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4 August 2017

page(s)

8969-8974

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Ca2+/calcineurin signalling in cells of the immune system

4 August 2017

cites work

1 reference

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Individuality: the barrier to optimal immunosuppression

8 July 2018

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Transcriptional regulation by calcium, calcineurin, and NFAT

8 July 2018

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The cellular and molecular basis of store-operated calcium entry

8 July 2018

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NFAT signaling: choreographing the social lives of cells

8 July 2018

1 reference

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The TRP ion channel family.

8 July 2018

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Gene regulation mediated by calcium signals in T lymphocytes

8 July 2018

1 reference

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Calcium, calcineurin, and the control of transcription

8 July 2018

1 reference

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c-Jun NH(2)-terminal kinase inhibits targeting of the protein phosphatase calcineurin to NFATc1.

8 July 2018

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Nucleocytoplasmic shuttling and the control of NF-AT signaling

8 July 2018

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Nuclear transport and transcription

8 July 2018

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TRP, inositol 1,4,5-trisphosphate receptors, and capacitative calcium entry

8 July 2018

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Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

8 July 2018

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The transcription factor NFAT4 is involved in the generation and survival of T cells

8 July 2018

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Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

8 July 2018

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Transcription factors of the NFAT family: regulation and function

8 July 2018

1 reference

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Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

8 July 2018

1 reference

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Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.

8 July 2018

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Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp)

8 July 2018

2 references

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8 July 2018

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Isolation of mutant T lymphocytes with defects in capacitative calcium entry

21 January 2018

1 reference

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Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels.

8 July 2018

1 reference

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Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

8 July 2018

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When worlds collide: immunosuppressants meet protein phosphatases

8 July 2018

1 reference

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Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.

8 July 2018

1 reference

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https://api.crossref.org/works/10.1073%2FPNAS.0402803101

Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0402803101

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0402803101

Signalling into the T-cell nucleus: NFAT regulation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15184684

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0402803101

1 reference

4 August 2017

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4 August 2017

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