Organic synthesis toward small-molecule probes and drugs (Q34880206)

5 August 2017

1 reference

title

Organic synthesis toward small-molecule probes and drugs (English)

1 reference

5 August 2017

Stuart L Schreiber

1

1 reference

PubMed ID

21464328

5 August 2017

language of work or name

English

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publication date

4 April 2011

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Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

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5 August 2017

108

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5 August 2017

6699-6702

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5 August 2017

17

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Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Complex synthesis yields breast-cancer therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Towards patient-based cancer therapeutics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Spiroindolones, a potent compound class for the treatment of malaria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Small-molecule inducers of insulin expression in pancreatic alpha-cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Thousands of chemical starting points for antimalarial lead identification

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

A complex task? Direct modulation of transcription factors with small molecules

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

A small molecule that binds Hedgehog and blocks its signaling in human cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Small-molecule inhibitors of protein-protein interactions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Towards the optimal screening collection: a synthesis strategy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

The Nobel chronicles. 1988: James Whyte Black, (b 1924), Gertrude Elion (1918-99), and George H Hitchings (1905-98).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Control of p70 s6 kinase by kinase activity of FRAP in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

The mechanism of action of colchicine. Colchicine binding to sea urchin eggs and the mitotic apparatus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Recent studies on the mode of action of scorpion neurotoxins. A review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Protein kinase C as the receptor for the phorbol ester tumor promoters: sixth Rhoads memorial award lecture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084057

Early psychopharmacology and the rise of modern brain research.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1103205108

Chemical genetics: where genetics and pharmacology meet

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1103205108

Chemical genetics resulting from a passion for synthetic organic chemistry.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1103205108

'Cure acceleration' funds woven into health reform legislation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21464328

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1103205108

1 reference

release_q2xjh62swrc4pkdz7rfuhewele

5 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/q2xjh62swrc4pkdz7rfuhewele

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3084057

1 reference

5 August 2017

1 reference

PubMed ID

21464328