Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor (Q28208226)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278746%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278746%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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1

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6 November 2019

author name string

Tabibzadeh S

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278746%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

language of work or name

English

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publication date

20 February 2001

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278746%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

6 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278746%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

276

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6 November 2019

issue

24

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6 November 2019

page(s)

21397-21404

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Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

6 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

A structural basis for mutational inactivation of the tumour suppressor Smad4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Smads: transcriptional activators of TGF-beta responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

TGF beta signals through a heteromeric protein kinase receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Mechanism of activation of the TGF-beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

A transcriptional partner for MAD proteins in TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor beta-induced smad-dependent transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Human Smad3 and Smad4 are sequence-specific transcription activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Transcriptional control by the TGF-beta/Smad signaling system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Silencing of TGF-beta signalling by the pseudoreceptor BAMBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Smad6 inhibits signalling by the TGF-beta superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Expression cloning of Xantivin, a Xenopus lefty/antivin-related gene, involved in the regulation of activin signaling during mesoderm induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Neural induction by the secreted polypeptide noggin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Biosynthesis, distinct post-translational modifications, and functional characterization of lymphoma proprotein convertase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Asymmetric expression of antivin/lefty1 in the early chick embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

The expression pattern of nodal and lefty in the mouse mutant Ft suggests a function in the establishment of handedness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Transforming growth factor-beta 3 is required for secondary palate fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Lefty proteins exhibit unique processing and activate the MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Smad2 role in mesoderm formation, left-right patterning and craniofacial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of nodal signaling required for organizer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Fast1 is required for the development of dorsal axial structures in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Distinct tumor specific expression of TGFB4 (ebaf)*, a novel human gene of the TGF-beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Isolation of human cDNA clones of ski and the ski-related gene, sno

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Transforming growth factor-beta1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Transforming growth factor-beta signaling in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

Activin- and Nodal-related factors control antero–posterior patterning of the zebrafish embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010783200

21 January 2018

Identifiers

DOI

10.1074/JBC.M010783200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278746%20AND%20SRC:MED&resulttype=core&format=json

release_dgdg5gw6ujfq7dom3yqqbpp25u

6 November 2019

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/dgdg5gw6ujfq7dom3yqqbpp25u

mapped directly with Wikidata item

24 November 2022

based on heuristic

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