Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease (Q34977478)

5 August 2017

title

Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease (English)

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5 August 2017

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1

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11 June 2020

Oliver Bandmann

series ordinal

3

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11 June 2020

author name string

Jan Aasly

series ordinal

2

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11 June 2020

language of work or name

English

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publication date

2 September 2013

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5 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24000005%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

136

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11 June 2020

issue

Pt 10

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11 June 2020

page(s)

3038-3050

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Expanding insights of mitochondrial dysfunction in Parkinson's disease.

11 June 2020

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Beta-synuclein regulates Akt activity in neuronal cells. A possible mechanism for neuroprotection in Parkinson's disease

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Dopaminergic expression of the Parkinsonian gene LRRK2-G2019S leads to non-autonomous visual neurodegeneration, accelerated by increased neural demands for energy.

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Mitochondrial neuronal uncoupling proteins: a target for potential disease-modification in Parkinson's disease

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Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease.

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mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass

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Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease

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The transgenic overexpression of alpha-synuclein and not its related pathology associates with complex I inhibition.

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RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation

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A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2

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LRRK2 directly phosphorylates Akt1 as a possible physiological substrate: impairment of the kinase activity by Parkinson's disease-associated mutations

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LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews.

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Identifiers

DOI

10.1093/BRAIN/AWT224

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24000005%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference