CSF-1R inhibition alters macrophage polarization and blocks glioma progression (Q34993852)

5 August 2017

CSF-1R inhibition alters macrophage polarization and blocks glioma progression (English)

1 reference

5 August 2017

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16

1 reference

5 August 2017

Oakley C Olson

7

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Leila Akkari

Leila Akkari

2

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Alberto J Schuhmacher

Alberto J Schuhmacher

3

0 references

Manu Setty

11

Manu Setty

1 reference

5 August 2017

6

Daniela F Quail

1 reference

5 August 2017

8

Marsha L Quick

1 reference

5 August 2017

9

Jason T Huse

1 reference

5 August 2017

20

Johanna A Joyce

1 reference

5 August 2017

Robert L Bowman

4

0 references

Eric C Holland

18

Eric C Holland

1 reference

5 August 2017

Stephanie M Pyonteck

1

1 reference

5 August 2017

Lisa Sevenich

5

1 reference

5 August 2017

Virginia Teijeiro

10

1 reference

5 August 2017

Christina S Leslie

12

1 reference

5 August 2017

Yoko Oei

13

1 reference

5 August 2017

Alicia Pedraza

14

1 reference

5 August 2017

Jianan Zhang

15

1 reference

5 August 2017

James C Sutton

17

1 reference

5 August 2017

Dylan Daniel

19

1 reference

5 August 2017

language of work or name

English

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publication date

22 September 2013

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5 August 2017

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5 August 2017

19

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5 August 2017

10

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5 August 2017

1264-1272

1 reference

https://scigraph.springernature.com/pub.10.1038/nm.3337

5 August 2017

0 references

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Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling

8 July 2018

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Differential macrophage programming in the tumor microenvironment

8 July 2018

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8 July 2018

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Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

8 July 2018

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Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits

8 July 2018

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Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

8 July 2018

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Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression

8 July 2018

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The role of SerpinB2 in immunity

8 July 2018

1 reference

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Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers

8 July 2018

1 reference

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Hallmarks of Cancer: The Next Generation

8 July 2018

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Genetic modeling of gliomas in mice: new tools to tackle old problems

8 July 2018

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Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas

8 July 2018

1 reference

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Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

8 July 2018

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Regularization Paths for Generalized Linear Models via Coordinate Descent

8 July 2018

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Glioma cancer stem cells induce immunosuppressive macrophages/microglia

8 July 2018

1 reference

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Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Colony-stimulating factor-1 receptor inhibitors for the treatment of cancer and inflammatory disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Modeling Adult Gliomas Using RCAS/t-va Technology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Microenvironmental regulation of metastasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Dynamics of central and peripheral immunomodulation in a murine glioma model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Genetically engineered mouse models of brain cancer and the promise of preclinical testing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Malignant gliomas in adults

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

8 July 2018

1 reference

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Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Revisiting the biological roles of PAI2 (SERPINB2) in cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Novel pro-survival functions of the Kruppel-like transcription factor Egr2 in promotion of macrophage colony-stimulating factor-mediated osteoclast survival downstream of the MEK/ERK pathway.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Colony-stimulating factor-1 in immunity and inflammation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Factor XIIIa-immunoreactivity in tumors of the central nervous system.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Investigation of correlation among safety biomarkers in serum, histopathological examination, and toxicogenomics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Gene expression profiling of gliomas strongly predicts survival

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Role of the INK4a locus in tumor suppression and cell mortality.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840724

Factor XIII-A is involved in the regulation of gene expression in alternatively activated human macrophages

26 October 2018

1 reference

12 December 2020

A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

1 reference

12 December 2020

Granulocyte-macrophage colony-stimulating factor (CSF) and macrophage CSF-dependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammation

1 reference

12 December 2020

Tumor-associated macrophages promote angiogenesis and melanoma growth via adrenomedullin in a paracrine and autocrine manner

1 reference

12 December 2020

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

1 reference

7 January 2021

Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma.

1 reference

7 January 2021

Inflammatory monocytes facilitate adaptive CD4 T cell responses during respiratory fungal infection.

1 reference

7 January 2021

Conditional macrophage ablation demonstrates that resident macrophages initiate acute peritoneal inflammation

1 reference

7 January 2021

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

1 reference

7 January 2021

Layer V cortical neurons require microglial support for survival during postnatal development.

1 reference

7 January 2021

'Green mice' as a source of ubiquitous green cells.

1 reference

7 January 2021

Long term culture of normal and neoplastic human glia.

1 reference

7 January 2021

Establishment of mononuclear phagocyte cell lines

1 reference

7 January 2021

An immortalized cell line expresses properties of activated microglial cells

1 reference

7 January 2021

Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

1 reference

7 January 2021

A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging

1 reference

7 January 2021

Strengths and limitations of the neurosphere culture system

1 reference

7 January 2021

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

1 reference

7 January 2021

MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo

1 reference

7 January 2021

Summaries of Affymetrix GeneChip probe level data

1 reference

7 January 2021

affy--analysis of Affymetrix GeneChip data at the probe level

1 reference

7 January 2021

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

1 reference

7 January 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM.3337

1 reference

Dimensions Publication ID

5 August 2017

0 references

1 reference

5 August 2017

1 reference