A sea of biosynthesis: marine natural products meet the molecular age. (Q35006338)

5 August 2017

1 reference

title

A sea of biosynthesis: marine natural products meet the molecular age. (English)

1 reference

5 August 2017

main subject

marine natural product

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1 reference

2

Bradley S Moore

1 reference

5 August 2017

Amy L Lane

1

1 reference

5 August 2017

publication date

17 December 2010

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5 August 2017

published in

Natural Product Reports

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5 August 2017

volume

28

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5 August 2017

issue

2

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5 August 2017

page(s)

411-428

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Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase

5 August 2017

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8 July 2018

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Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.

8 July 2018

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PKS and NRPS release mechanisms

8 July 2018

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Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation

8 July 2018

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Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide.

8 July 2018

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Functional characterization of the cyclomarin/cyclomarazine prenyltransferase CymD directs the biosynthesis of unnatural cyclic peptides.

8 July 2018

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Insights into the evolution of macrolactam biosynthesis through cloning and comparative analysis of the biosynthetic gene cluster for a novel macrocyclic lactam, ML-449

8 July 2018

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8 July 2018

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Genomic basis for natural product biosynthetic diversity in the actinomycetes

8 July 2018

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Function-oriented biosynthesis of beta-lactone proteasome inhibitors in Salinispora tropica

8 July 2018

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Mechanistic considerations of halogenating enzymes

8 July 2018

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8 July 2018

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Structural insights into nonribosomal peptide enzymatic assembly lines

8 July 2018

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New natural product biosynthetic chemistry discovered by genome mining

8 July 2018

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Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity.

8 July 2018

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8 July 2018

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The biosynthetic logic of polyketide diversity

8 July 2018

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8 July 2018

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8 July 2018

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Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria

8 July 2018

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8 July 2018

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Biosynthesis of polyketide synthase extender units

8 July 2018

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Recent advances in siderophore biosynthesis

8 July 2018

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Exploring the chemistry and biology of vanadium-dependent haloperoxidases

8 July 2018

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Genomic mining--a concept for the discovery of new bioactive natural products

8 July 2018

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Metabolites from symbiotic bacteria

8 July 2018

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In vitro biosynthesis of unnatural enterocin and wailupemycin polyketides

8 July 2018

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Heterologous expression systems for polyketide synthases

8 July 2018

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Drug development from marine natural products

8 July 2018

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Isoprenoid-like alkylations in polyketide biosynthesis

8 July 2018

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Structural perspective on enzymatic halogenation

8 July 2018

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The fluorinase, the chlorinase and the duf-62 enzymes

8 July 2018

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Trading molecules and tracking targets in symbiotic interactions

8 July 2018

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Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome

8 July 2018

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Genome mining for novel natural product discovery

8 July 2018

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Discovery and characterization of a marine bacterial SAM-dependent chlorinase

8 July 2018

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Systems biology of antibiotic production by microorganisms

8 July 2018

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GNAT-like strategy for polyketide chain initiation

8 July 2018

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Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching

8 July 2018

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Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica

8 July 2018

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Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster

8 July 2018

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Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork

8 July 2018

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Identification of the putative bryostatin polyketide synthase gene cluster from "Candidatus Endobugula sertula", the uncultivated microbial symbiont of the marine bryozoan Bugula neritina

8 July 2018

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The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis

8 July 2018

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Species-specific secondary metabolite production in marine actinomycetes of the genus Salinispora

8 July 2018

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Structural biology and chemistry of the terpenoid cyclases

8 July 2018

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Nature's inventory of halogenation catalysts: oxidative strategies predominate

8 July 2018

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Biosynthesis of marine natural products: macroorganisms (Part B).

8 July 2018

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Convergence of isoprene and polyketide biosynthetic machinery: isoprenyl-S-carrier proteins in the pksX pathway of Bacillus subtilis

8 July 2018

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Structure of trichamide, a cyclic peptide from the bloom-forming cyanobacterium Trichodesmium erythraeum, predicted from the genome sequence.

8 July 2018

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The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites

8 July 2018

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Bacterial symbionts: prospects for the sustainable production of invertebrate-derived pharmaceuticals

8 July 2018

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Biosynthesis of marine natural products: microorganisms (Part A).

8 July 2018

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From chemical structure to environmental biosynthetic pathways: navigating marine invertebrate-bacteria associations

8 July 2018

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SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase

8 July 2018

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Shotgun cloning and heterologous expression of the patellamide gene cluster as a strategy to achieving sustained metabolite production

8 July 2018

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Biochemical characterization of a prokaryotic phenylalanine ammonia lyase

8 July 2018

1 reference

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Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella

8 July 2018

1 reference

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Vanadium bromoperoxidase-catalyzed biosynthesis of halogenated marine natural products

8 July 2018

1 reference

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Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins.

8 July 2018

1 reference

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Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei

8 July 2018

1 reference

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EncM, a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement, aldol condensation, and heterocycle-forming reactions

8 July 2018

1 reference

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Biosynthesis of nonribosomal peptides1.

8 July 2018

1 reference

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Lyngbyatoxin biosynthesis: sequence of biosynthetic gene cluster and identification of a novel aromatic prenyltransferase

8 July 2018

1 reference

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Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula

8 July 2018

1 reference

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Genetic evidence supports secondary metabolic diversity in Prochloron spp., the cyanobacterial symbiont of a tropical ascidian

8 July 2018

1 reference

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Marine natural products and related compounds in clinical and advanced preclinical trials

8 July 2018

1 reference

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Metabolites from symbiotic bacteria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula

8 July 2018

1 reference

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Psymberin, a potent sponge-derived cytotoxin from Psammocinia distantly related to the pederin family

8 July 2018

1 reference

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The role of vanadium bromoperoxidase in the biosynthesis of halogenated marine natural products

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

Polyketide and nonribosomal peptide antibiotics: modularity and versatility

8 July 2018

1 reference

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Crystal structure and mechanism of a bacterial fluorinating enzyme

8 July 2018

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Diversity of the biosynthesis of the isoprene units

8 July 2018

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Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

8 July 2018

1 reference

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Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora.

8 July 2018

1 reference

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Characterization of benzoyl coenzyme A biosynthesis genes in the enterocin-producing bacterium "Streptomyces maritimus"

8 July 2018

1 reference

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The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

Molecular evidence for a uniform microbial community in sponges from different oceans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

Biosynthesis and attachment of novel bacterial polyketide synthase starter units

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

The Pfam protein families database

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

How many antibiotics are produced by the genus Streptomyces?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

Polyketide biosynthesis: a millennium review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

GeneMarkS: a self-training method for prediction of gene starts in microbial genomes. Implications for finding sequence motifs in regulatory regions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

Biosynthesis of fatty acids in the docosahexaenoic acid-producing bacterium Moritella marina strain MP-1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

TIGRFAMs: a protein family resource for the functional identification of proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

Structural organization of microcystin biosynthesis in Microcystis aeruginosa PCC7806: an integrated peptide-polyketide synthetase system.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

Highlights of marine natural products chemistry (1972-1999).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

New cyclic peptides with cytotoxic activity from the ascidian Lissoclinum patella.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

The biosynthesis of triterpenoids, steroids, and carotenoids

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

Biosynthesis of polyketide metabolites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101795

4-[2-(2-amino-2-oxoethyl)-2,7-dihydroxy-4-oxochroman-5-yl]-3-hydroxybut-2-enoic acid

8 July 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Chapter 23. Cyanobactin ribosomally synthesized peptides--a case of deep metagenome mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Molecular mechanisms underlying nonribosomal peptide synthesis: approaches to new antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Context-dependent behavior of the enterocin iterative polyketide synthase; a new model for ketoreduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Mutasynthesis of enterocin and wailupemycin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Inactivation, complementation, and heterologous expression of encP, a novel bacterial phenylalanine ammonia-lyase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Engineered biosynthesis of antiprotealide and other unnatural salinosporamide proteasome inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Unraveling the biosynthesis of the sporolide cyclohexenone building block.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Privileged structures as leads in medicinal chemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Analysis of the sorangicin gene cluster reinforces the utility of a combined phylogenetic/retrobiosynthetic analysis for deciphering natural product assembly by trans-AT PKS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Pederin-type pathways of uncultivated bacterial symbionts: analysis of o-methyltransferases and generation of a biosynthetic hybrid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Localization studies of ioactive cyclic peptides in the ascidian Lissoclinum patella.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Natural Organohalogens: A New Frontier for Medicinal Agents?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Biosynthesis and structures of cyclomarins and cyclomarazines, prenylated cyclic peptides of marine actinobacterial origin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Structure and regulation of the omega-3 polyunsaturated fatty acid synthase genes from the deep-sea bacterium Photobacterium profundum strain SS9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NP90032J

Mutational analysis of the enterocin favorskii biosynthetic rearrangement

21 January 2018

1 reference

12 December 2020

A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A

1 reference

12 December 2020

New cyclic peptides from the ascidian Lissoclinum patella

1 reference

12 December 2020

Halogenation of unactivated carbon centers in natural product biosynthesis: trichlorination of leucine during barbamide biosynthesis

1 reference

12 December 2020

Characterization of the initial enzymatic steps of barbamide biosynthesis

1 reference

12 December 2020

Enzymatic total synthesis of enterocin polyketides

1 reference

12 December 2020

Complex enzymes in microbial natural product biosynthesis, part B: polyketides, aminocoumarins and carbohydrates. Preface

1 reference

12 December 2020

Marine natural products

1 reference

12 December 2020

Identifiers

DOI

10.1039/C0NP90032J

1 reference

release_pzsftozcxjftrk36he3yoa7fwe

5 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pzsftozcxjftrk36he3yoa7fwe

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3101795

1 reference

5 August 2017

1 reference