Similarities between the Hedgehog and Wnt signaling pathways (Q35006446)

5 August 2017

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title

Similarities between the Hedgehog and Wnt signaling pathways (English)

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5 August 2017

Daniel Kalderon

1

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5 August 2017

1 November 2002

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5 August 2017

Trends in Cell Biology

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5 August 2017

12

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5 August 2017

11

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5 August 2017

523-531

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New aspects of Wnt signaling pathways in higher vertebrates

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Hedgehog signaling in animal development: paradigms and principles

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The Hedgehog and Wnt signalling pathways in cancer

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The ballet of morphogenesis: unveiling the hidden choreographers

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The low-density lipoprotein receptor gene family: a cellular Swiss army knife?

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Megalin functions as an endocytic sonic hedgehog receptor

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Planar signaling and morphogenesis in Drosophila

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Patched acts catalytically to suppress the activity of Smoothened

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The sterol-sensing domain: multiple families, a unique role?

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Sonic hedgehog induces the segregation of patched and smoothened in endosomes

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Activation of a frizzled-2/beta-adrenergic receptor chimera promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via Galphao and Galphat

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

G protein signaling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Dishevelled: at the crossroads of divergent intracellular signaling pathways

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The dishevelled protein is modified by wingless signaling in Drosophila

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis.

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Smoothened activates Galphai-mediated signaling in frog melanophores

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Casein kinase I transduces Wnt signals

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Wnt signaling controls the phosphorylation status of beta-catenin.

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Regulation of the protein kinase activity of Shaggy(Zeste-white3) by components of the wingless pathway in Drosophila cells and embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Identification of a tetrameric hedgehog signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Genetic dissection of the Drosophila Cubitus interruptus signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Drosophila Roc1a encodes a RING-H2 protein with a unique function in processing the Hh signal transducer Ci by the SCF E3 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Mechanisms of ubiquitin-mediated, limited processing of the NF-kappaB1 precursor protein p105.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Adhesion signaling: how beta-catenin interacts with its partners

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The subcellular destinations of APC proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

The APC tumour suppressor has a nuclear export function.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Getting legless with a Pygopus.

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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

Suppressor of fused negatively regulates beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7

7 January 2021

10.1016/S0962-8924(02)02388-7

Identifiers

DOI

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5 August 2017

1 reference

PubMed ID

12446114