The alpha v integrin antagonists as novel anticancer agents: an update (Q35011900)

5 August 2017

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title

The alpha v integrin antagonists as novel anticancer agents: an update (English)

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5 August 2017

Janet S Kerr

1

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5 August 2017

Andrew M Slee

series ordinal

2

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5 August 2017

Shaker A Mousa

series ordinal

3

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5 August 2017

language of work or name

English

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publication date

1 December 2002

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Expert Opinion on Investigational Drugs

5 August 2017

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5 August 2017

11

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5 August 2017

1765-1774

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5 August 2017

12

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Arg-Gly-Asp: a versatile cell recognition signal

5 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Integrins: versatility, modulation, and signaling in cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

The pharmacology of the integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Molecular role(s) for integrins in human melanoma invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

A link between cyclin A expression and adhesion-dependent cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Signal transduction from the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Integrins: bidirectional, allosteric signaling machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Mechanisms of tumour invasion and metastasis: emerging targets for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Angiogenesis and tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Integrins and GTPases in tumour cell growth, motility and invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

21 January 2018

Integrins and anoikis

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Integrins and vascular extracellular matrix assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Role of integrins in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Crystal structure of the extracellular segment of integrin alpha Vbeta3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Involvement of integrin alpha V gene expression in human melanoma tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Role of V Integrins and Vitronectin in Human Melanoma Cell Growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Role of the alpha v beta 3 integrin in human melanoma cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Integrin activation controls metastasis in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Cilengitide targeting of alpha(v)beta(3) integrin receptor synergizes with radioimmunotherapy to increase efficacy and apoptosis in breast cancer xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Comparative analysis of integrins in vitro and in vivo in uveal and cutaneous melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Steps toward mapping the human vasculature by phage display.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Targeting the prostate for destruction through a vascular address

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Imaging of metastatic melanoma utilising a technetium-99m labelled RGD-containing synthetic peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

A pilot trial of Vitaxin, a humanized anti-vitronectin receptor (anti alpha v beta 3) antibody in patients with metastatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Integrin chatter and vascular function in diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Requirement of vascular integrin alpha v beta 3 for angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

A reevaluation of integrins as regulators of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

In vitro and in vivo effects of a cyclic peptide with affinity for the alpha(nu)beta3 integrin in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Identification and in vivo efficacy of small-molecule antagonists of integrin alphavbeta3 (the vitronectin receptor).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

Extracellular Matrix-derived Peptide Binds to αvβ3Integrin and Inhibits Angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.12.1765

10.1517/13543784.11.12.1765

21 January 2018

Identifiers

DOI

1 reference

5 August 2017

1 reference