Chemotherapy: targeting the mitochondrial cell death pathway (Q35026496)

5 August 2017

1 reference

title

Chemotherapy: targeting the mitochondrial cell death pathway (English)

1 reference

5 August 2017

1 reference

1 reference

3

Guido Kroemer

0 references

Klaus-Michael Debatin

series ordinal

1

object named as

Klaus-Michael Debatin

0 references

author name string

Delphine Poncet

series ordinal

2

1 reference

PubMed ID

12483532

5 August 2017

language of work or name

English

0 references

publication date

1 December 2002

1 reference

5 August 2017

1 reference

5 August 2017

21

1 reference

5 August 2017

57

1 reference

5 August 2017

8786-8803

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206039

5 August 2017

0 references

cites work

Targeting the prostate for destruction through a vascular address

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

Life-or-death decisions by the Bcl-2 protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Interleukin 2-Bax: a novel prototype of human chimeric proteins for targeted therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Steps toward mapping the human vasculature by phage display.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

PK11195, a peripheral benzodiazepine receptor ligand, chemosensitizes acute myeloid leukemia cells to relevant therapeutic agents by more than one mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Cytotoxic T lymphocytes: all roads lead to death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Pro-apoptotic cleavage products of Bcl-xL form cytochrome c-conducting pores in pure lipid membranes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Apoptosis-inducing human-origin Fcepsilon-Bak chimeric proteins for targeted elimination of mast cells and basophils: a new approach for allergy treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

A mitochondrial perspective on cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Ikappa b-alpha, the NF-kappa B inhibitory subunit, interacts with ANT, the mitochondrial ATP/ADP translocator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Biochemical pathways of caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Peripheral benzodiazepine receptors and mitochondrial function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

BCL-2 family: regulators of cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondrial Membrane Potential in Living Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondrial intermembrane junctional complexes and their role in cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Cells bearing mutations causing Leber's hereditary optic neuropathy are sensitized to Fas-Induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Paclitaxel, cisplatin and lonidamine in advanced ovarian cancer. A phase II study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Palmitate induces apoptosis via a direct effect on mitochondria.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Anti-cancer activity of targeted pro-apoptotic peptides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Organelle-specific initiation of cell death pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Betulinic acid induces apoptosis through a direct effect on mitochondria in neuroectodermal tumors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Activation of Mitochondria and Release of Mitochondrial Apoptogenic Factors by Betulinic Acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Expression of human ANT2 gene in highly proliferative cells: GRBOX, a new transcriptional element, is involved in the regulation of glycolytic ATP import into mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Hexokinase binding to mitochondria: a basis for proliferative energy metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The central executioners of apoptosis: caspases or mitochondria?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

tBID Homooligomerizes in the mitochondrial membrane to induce apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-kappaB by inhibiting both its nuclear localization and ability to bind DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Cellular stress response and apoptosis in cancer therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Arsenite induces apoptosis of murine T lymphocytes through membrane raft-linked signaling for activation of c-Jun amino-terminal kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Chemosensitisation of malignant melanoma by BCL2 antisense therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Apoptosis: a link between cancer genetics and chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Genetic analysis of the mammalian cell death machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The role of the peripheral benzodiazepine receptor in the apoptotic response to photodynamic therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Paclitaxel affects cytosolic calcium signals by opening the mitochondrial permeability transition pore

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The biochemistry of programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondrial control of cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The Destabilization of Lipid Membranes Induced by the C-terminal Fragment of Caspase 8-cleaved Bid Is Inhibited by the N-terminal Fragment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Targeting of the c-Abl tyrosine kinase to mitochondria in the necrotic cell death response to oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Endonuclease G is an apoptotic DNase when released from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Cardiolipin provides specificity for targeting of tBid to mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

S-Nitrosylation of mitochondrial caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Breaking the mitochondrial barrier

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondrial lipid alterations during Fas- and radiation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Potentiation of lonidamine and diazepam, two agents acting on mitochondria, in human glioblastoma treatment.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Adenovirus encoding HIV-1 Vpr activates caspase 9 and induces apoptotic cell death in both p53 positive and negative human tumor cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Immunosuppressant FTY720 induces apoptosis by direct induction of permeability transition and release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondrial phospholipid hydroperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Cytochrome c release from mitochondria proceeds by a two-step process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Expression of apoptosis-related markers and clinical outcome in patients with advanced colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Heat-shock protein 70 antagonizes apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Distinct pathways for stimulation of cytochrome c release by etoposide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

BAX-dependent transport of cytochrome c reconstituted in pure liposomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Alloxan-induced mitochondrial permeability transition triggered by calcium, thiol oxidation, and matrix ATP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Ion channel activity of the BH3 only Bcl-2 family member, BID.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondrial creatine kinase and mitochondrial outer membrane porin show a direct interaction that is modulated by calcium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-alpha aopototic signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondrial DNA determines the cellular response to cancer therapeutic agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Transient protection by peripheral benzodiazepine receptors during the early events of ultraviolet light-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: high BAX and p16(ink4a/CDKN2) identifies patients with good prognosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Mitochondrial release of caspase-2 and -9 during the apoptotic process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

BAX protein expression and clinical outcome in epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Anti-apoptotic effect of cGMP in cultured astrocytes: inhibition by cGMP-dependent protein kinase of mitochondrial permeable transition pore

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Growth factors can influence cell growth and survival through effects on glucose metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-X(L).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Increased in vivo apoptosis in cells lacking mitochondrial DNA gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

On the Origin of Cancer Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Photochemical destruction of the Bcl-2 oncoprotein during photodynamic therapy with the phthalocyanine photosensitizer Pc 4.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Molecular mechanisms of butylated hydroxylanisole-induced toxicity: induction of apoptosis through direct release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Bid acts on the permeability transition pore complex to induce apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The mitochondrion in apoptosis: how Pandora's box opens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

The mitochondrial permeability transition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206039

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206039

1 reference

5 August 2017

1 reference

PubMed ID

12483532