Prdm16 is a physiologic regulator of hematopoietic stem cells. (Q35029415)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21343612%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Prdm16 is a physiologic regulator of hematopoietic stem cells (English)

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23 January 2020

1

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23 January 2020

Ana Sevilla

4

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23 January 2020

Dung-Fang Lee

5

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23 January 2020

author name string

Serine Avagyan

2

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23 January 2020

Amy Labar

3

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23 January 2020

Parameet Kumar

6

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23 January 2020

Ihor R Lemischka

7

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23 January 2020

Betty Y Zhou

8

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23 January 2020

Hans-Willem Snoeck

9

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language of work or name

English

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publication date

22 February 2011

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23 January 2020

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23 January 2020

volume

117

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23 January 2020

issue

19

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23 January 2020

page(s)

5057-5066

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The p53 tumor suppressor protein regulates hematopoietic stem cell fate

23 January 2020

cites work

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Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress

8 July 2018

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Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation

8 July 2018

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Deletion of Puma protects hematopoietic stem cells and confers long-term survival in response to high-dose gamma-irradiation.

8 July 2018

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Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells

8 July 2018

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Ryks: new partners for Wnts in the developing and regenerating nervous system

8 July 2018

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Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex

8 July 2018

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

8 July 2018

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A functional screen to identify novel effectors of hematopoietic stem cell activity

8 July 2018

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p53 regulates hematopoietic stem cell quiescence.

8 July 2018

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Mouse hematopoietic stem cell identification and analysis

8 July 2018

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PRDM16 controls a brown fat/skeletal muscle switch

8 July 2018

1 reference

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Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells.

8 July 2018

1 reference

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Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence.

8 July 2018

1 reference

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Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells

8 July 2018

1 reference

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Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors

8 July 2018

1 reference

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The Bax Inhibitor-1 (BI-1) family in apoptosis and tumorigenesis

8 July 2018

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Hematopoiesis: an evolving paradigm for stem cell biology

8 July 2018

1 reference

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Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice

8 July 2018

1 reference

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The protean nature of cells in the B lymphocyte lineage

8 July 2018

1 reference

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Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice

8 July 2018

1 reference

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Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors

8 July 2018

1 reference

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The antioxidant function of the p53 tumor suppressor

8 July 2018

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Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells

8 July 2018

1 reference

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Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche

8 July 2018

1 reference

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Quantitative trait analysis reveals transforming growth factor-beta2 as a positive regulator of early hematopoietic progenitor and stem cell function

8 July 2018

1 reference

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Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

8 July 2018

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A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation

8 July 2018

1 reference

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Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

8 July 2018

1 reference

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CD34 expression on long-term repopulating hematopoietic stem cells changes during developmental stages

8 July 2018

1 reference

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A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells

8 July 2018

1 reference

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

8 July 2018

1 reference

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

8 July 2018

1 reference

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An early haematopoietic defect in mice lacking the transcription factor GATA-2

8 July 2018

1 reference

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Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

8 July 2018

1 reference

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Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109532

Functional differences between two Tie2 ligands, angiopoietin-1 and -2, in regulation of adult bone marrow hematopoietic stem cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109532

Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109532

RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109532

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109532

Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4-/- chimeric mice.

25 October 2018

1 reference

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Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109532

Definitive hematopoiesis requires the mixed-lineage leukemia gene

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109532

Stem cell repopulation efficiency but not pool size is governed by p27(kip1).

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109532

A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression.

25 October 2018

1 reference

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Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

25 October 2018

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12 December 2020

Novel RUNX1-PRDM16 fusion transcripts in a patient with acute myeloid leukemia showing t(1;21)(p36;q22)

1 reference

12 December 2020

Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation

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12 December 2020

Identification and In Vivo Analysis of Murine Hematopoietic Stem Cells

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12 December 2020

Hematopoietic stem cell quiescence maintained by p21cip1/waf1

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12 December 2020

Fluidigm. Biochips get indoor plumbing

1 reference

12 December 2020

Thymopoiesis independent of common lymphoid progenitors

1 reference

12 December 2020

10.1182/BLOOD-2010-08-300145

Identifiers

DOI

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23 January 2020

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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23 January 2020

PubMed publication ID

21343612

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