Cancer immunotherapy: the role regulatory T cells play and what can be done to overcome their inhibitory effects. (Q35033249)

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5 February 2020

review article

1 reference

title

Cancer immunotherapy: the role regulatory T cells play and what can be done to overcome their inhibitory effects (English)

1 reference

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5 February 2020

1 reference

3

1 reference

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23

Bernard A Fox

1 reference

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5 February 2020

author name string

Ulf Petrausch

1

1 reference

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5 February 2020

Christian H Poehlein

2

1 reference

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5 February 2020

Chris Twitty

4

1 reference

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5 February 2020

James A Thompson

5

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5 February 2020

Ilka Assmann

6

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5 February 2020

Sachin Puri

7

1 reference

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5 February 2020

Michael G LaCelle

8

1 reference

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Tarsem Moudgil

9

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Levi Maston

10

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5 February 2020

Kevin Friedman

11

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5 February 2020

Sarah Church

12

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5 February 2020

Elisa Cardenas

13

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5 February 2020

Daniel P Haley

14

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5 February 2020

Edwin B Walker

15

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5 February 2020

Emmanuel Akporiaye

16

1 reference

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5 February 2020

Andrew D Weinberg

17

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5 February 2020

Sidney Rosenheim

18

1 reference

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5 February 2020

Todd S Crocenzi

19

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5 February 2020

Hong-Ming Hu

20

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5 February 2020

Brendan D Curti

21

1 reference

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Walter J Urba

22

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publication date

1 August 2009

1 reference

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Current Molecular Medicine

5 February 2020

published in

1 reference

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volume

9

1 reference

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issue

6

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5 February 2020

page(s)

673-682

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Treg depletion inhibits efficacy of cancer immunotherapy: implications for clinical trials

5 February 2020

cites work

1 reference

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OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection

8 July 2018

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Transient T cell depletion causes regression of melanoma metastases

8 July 2018

1 reference

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Human lymphocyte activation gene-3 molecules expressed by activated T cells deliver costimulation signal for dendritic cell activation

8 July 2018

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Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activation

8 July 2018

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The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy

8 July 2018

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The genomic landscapes of human breast and colorectal cancers

8 July 2018

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Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance

8 July 2018

1 reference

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Administration of a CD25-directed immunotoxin, LMB-2, to patients with metastatic melanoma induces a selective partial reduction in regulatory T cells in vivo

8 July 2018

1 reference

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Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40

8 July 2018

1 reference

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Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma

8 July 2018

1 reference

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IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells

8 July 2018

1 reference

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Adjuvant therapeutic vaccination in patients with non-small cell lung cancer made lymphopenic and reconstituted with autologous PBMC: first clinical experience and evidence of an immune response

8 July 2018

1 reference

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Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor.

8 July 2018

1 reference

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OX40 costimulation turns off Foxp3+ Tregs.

8 July 2018

1 reference

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

8 July 2018

1 reference

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Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.

8 July 2018

1 reference

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IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells

8 July 2018

1 reference

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Treatment-enhanced CD4+Foxp3+ glucocorticoid-induced TNF receptor family related high regulatory tumor-infiltrating T cells limit the effectiveness of cytokine-based immunotherapy

8 July 2018

1 reference

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Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

8 July 2018

1 reference

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Regulatory T cells and cancer

8 July 2018

1 reference

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Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment

8 July 2018

1 reference

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Increase in circulating Foxp3+CD4+CD25(high) regulatory T cells in nasopharyngeal carcinoma patients

8 July 2018

1 reference

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CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer

8 July 2018

1 reference

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Increased intensity lymphodepletion and adoptive immunotherapy--how far can we go?

8 July 2018

1 reference

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A mutant chaperone converts a wild-type protein into a tumor-specific antigen

8 July 2018

1 reference

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Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

8 July 2018

1 reference

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Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

8 July 2018

1 reference

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Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation

8 July 2018

1 reference

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Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells

8 July 2018

1 reference

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Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

8 July 2018

1 reference

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Selective elimination of human regulatory T lymphocytes in vitro with the recombinant immunotoxin LMB-2.

8 July 2018

1 reference

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Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

8 July 2018

1 reference

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Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

8 July 2018

1 reference

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Regulatory T cells in ovarian cancer: biology and therapeutic potential

8 July 2018

1 reference

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

8 July 2018

1 reference

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Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma

8 July 2018

1 reference

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Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines

8 July 2018

1 reference

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Leveraging the activity of tumor vaccines with cytotoxic chemotherapy

8 July 2018

1 reference

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TGF-β signaling in T cells: roles in lymphoid and epithelial neoplasia

8 July 2018

1 reference

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Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells

8 July 2018

1 reference

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T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

8 July 2018

1 reference

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Role of LAG-3 in regulatory T cells.

8 July 2018

1 reference

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Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

8 July 2018

1 reference

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GITR activation induces an opposite effect on alloreactive CD4(+) and CD8(+) T cells in graft-versus-host disease

8 July 2018

1 reference

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IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

8 July 2018

1 reference

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Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

8 July 2018

1 reference

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A phase I vaccine safety and chemotherapy dose-finding trial of an allogeneic GM-CSF-secreting breast cancer vaccine given in a specifically timed sequence with immunomodulatory doses of cyclophosphamide and doxorubicin

8 July 2018

1 reference

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CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative

8 July 2018

1 reference

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

8 July 2018

1 reference

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Cancer; a biological approach. I. The processes of control

8 July 2018

1 reference

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Foxp3 and natural regulatory T cells: key to a cell lineage?

8 July 2018

1 reference

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Natural versus adaptive regulatory T cells

8 July 2018

1 reference

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Control of regulatory T cell development by the transcription factor Foxp3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Tumor lysate-pulsed dendritic cells can elicit an effective antitumor immune response during early lymphoid recovery

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

8 July 2018

1 reference

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Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Divergent roles for CD4+ T cells in the priming and effector/memory phases of adoptive immunotherapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Role of OX40 signals in coordinating CD4 T cell selection, migration, and cytokine differentiation in T helper (Th)1 and Th2 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Presence of the T-cell activation marker OX-40 on tumor infiltrating lymphocytes and draining lymph node cells from patients with melanoma and head and neck cancers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Adverse and beneficial immunological effects of purine nucleoside analogues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Increased sensitivity of tumor-bearing host macrophages to interleukin-10: a counter-balancing action to macrophage-mediated suppression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Alternating noncross-resistant combination chemotherapy and active nonspecific immunotherapy with BCG or MER-BCG for advanced breast carcinoma.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

The concept of immunological surveillance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Augmentation of delayed-type hypersensitivity by doses of cyclophosphamide which do not affect antibody responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Treatment of advanced breast cancer with cyclophosphamide, 5-fluorouracil, and prednisone with and without methanol-extracted residue of BCG

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Suppressor Cells: Permitters and Promoters of Malignancy?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Neoadjuvant chemotherapy with reduced-dose carboplatin and gemcitabine for non-small cell lung cancer in a patient with Fanconi anemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Costimulatory strength influences the differential effects of transforming growth factor beta1 for the generation of CD8+ regulatory T cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Regulatory-T-cell inhibition versus depletion: the right choice in cancer immunotherapy

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

In vitro expansion of CD4+CD25highFOXP3+CD127low/- regulatory T cells from peripheral blood lymphocytes of healthy Mycobacterium tuberculosis-infected humans

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Functional and phenotypic characteristics of CD4+CD25highFoxp3+ Treg clones obtained from peripheral blood of patients with cancer

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Antigen, in the presence of TGF-beta, induces up-regulation of FoxP3gfp+ in CD4+ TCR transgenic T cells that mediate linked suppression of CD8+ T cell responses.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

CD4(+)CD25hi regulatory T-cell frequency correlates with persistence of human papillomavirus type 16 and T helper cell responses in patients with cervical intraepithelial neoplasia

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS).

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

CD4+ CD25+ FoxP3+ T-cell infiltration and heme oxygenase-1 expression correlate with tumor grade in human gliomas

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Human CD4+CD25+ regulatory T cells selectively express tyrosine hydroxylase and contain endogenous catecholamines subserving an autocrine/paracrine inhibitory functional loop.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

In vivo depletion of CD4+CD25+ regulatory T cells enhances the antigen-specific primary and memory CTL response elicited by mature mRNA-electroporated dendritic cells.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Triggering of OX40 (CD134) on CD4(+)CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Suppressive properties of human CD4+CD25+ regulatory T cells are dependent on CTLA-4 expression

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

A signal through OX40 (CD134) allows anergic, autoreactive T cells to acquire effector cell functions

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Immunopharmacologic analysis of an autologous, hapten-modified human melanoma vaccine

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Development of antitumor immune responses in reconstituted lymphopenic hosts.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Significant correlation between interleukin 10 expression and vascularization through angiopoietin/TIE2 networks in non-small cell lung cancer.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110749

Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients

9 December 2018

1 reference

12 December 2020

Severe immunodeficiency in patients treated with fludarabine monophosphate

1 reference

12 December 2020

Cutting edge: OX40 inhibits TGF-beta- and antigen-driven conversion of naive CD4 T cells into CD25+Foxp3+ T cells

1 reference

12 December 2020

Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance

1 reference

12 December 2020

Clinical roles of increased populations of Foxp3+CD4+ T cells in peripheral blood from advanced pancreatic cancer patients

1 reference

12 December 2020

A pilot study of the liposomal MUC1 vaccine BLP25 in prostate specific antigen failures after radical prostatectomy

1 reference

12 December 2020

CD4+CD25+ regulatory T-cell frequency in HER-2/neu (HER)-positive and HER-negative advanced-stage breast cancer patients

1 reference

12 December 2020

Induction of cell-mediated immunity to autologous melanoma cells and regression of metastases after treatment with a melanoma cell vaccine preceded by cyclophosphamide

1 reference

12 December 2020

Plasmacytoid DCs and T(reg) cells: casual acquaintance or monogamous relationship?

1 reference

12 December 2020

Enhancement of delayed hypersensitivity by depletion of suppressor T cells with cyclophosphamide in mice

1 reference

12 December 2020

Steady state dendritic cells with forced IDO expression induce skin allograft tolerance by upregulation of regulatory T cells

1 reference

12 December 2020

Differential regulation of tumor necrosing factor-alpha (TNF-alpha) and interleukin-10 (IL-10) secretion by protein kinase and phosphatase inhibitors in human alveolar macrophages

1 reference

12 December 2020

Reversal of immunological tolerance by cyclophosphamide through inhibition of suppressor cell activity

1 reference

12 December 2020

Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors

1 reference

12 December 2020

Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients

1 reference

12 December 2020

Improving T cell therapy for cancer

1 reference

12 December 2020

Danger and OX40 receptor signaling synergize to enhance memory T cell survival by inhibiting peripheral deletion

1 reference

12 December 2020

Combination of transient lymphodepletion with busulfan and fludarabine and peptide vaccination in a phase I clinical trial for patients with advanced melanoma

1 reference

12 December 2020

CD4+CD25+ regulatory T cells that secrete TGFbeta and IL-10 are preferentially induced by a vaccine vector

1 reference

12 December 2020

Depletion of CD4+ CD25+ regulatory cells augments the generation of specific immune T cells in tumor-draining lymph nodes

1 reference

12 December 2020

A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment

1 reference

12 December 2020

10.2174/156652409788970670

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19689294%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19689294%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

19689294

1 reference