Atorvastatin reverses age-related reduction in rat hepatic PPARalpha and HNF-4 (Q35049044)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912134%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Atorvastatin reverses age-related reduction in rat hepatic PPARalpha and HNF-4 (English)

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12 January 2020

2

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12 January 2020

Marta Alegret

3

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12 January 2020

Juan C. Laguna

6

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12 January 2020

author name string

Elena Sanguino

1

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12 January 2020

Rosa M Sánchez

4

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12 January 2020

Manuel Vázquez-Carrera

5

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12 January 2020

language of work or name

English

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publication date

1 August 2005

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British Journal of Pharmacology

12 January 2020

published in

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12 January 2020

volume

145

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12 January 2020

issue

7

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12 January 2020

page(s)

853-861

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Invited Review: Aging and the cardiovascular system

12 January 2020

cites work

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The coactivator PGC-1 is involved in the regulation of the liver carnitine palmitoyltransferase I gene expression by cAMP in combination with HNF4 alpha and cAMP-response element-binding protein (CREB)

8 July 2018

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PPARalpha deficiency increases secretion and serum levels of apolipoprotein B-containing lipoproteins

8 July 2018

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Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I

8 July 2018

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Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

8 July 2018

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8 July 2018

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Enhanced DNA binding and activation of transcription factors NF-kappa B and AP-1 by acetaldehyde in HEPG2 cells

8 July 2018

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Different effect of simvastatin and atorvastatin on key enzymes involved in VLDL synthesis and catabolism in high fat/cholesterol fed rabbits

8 July 2018

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Quantitative RT-PCR: pitfalls and potential

8 July 2018

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Comparison of statins in hypertriglyceridemia

8 July 2018

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Atorvastatin. A review of its pharmacology and therapeutic potential in the management of hyperlipidaemias

8 July 2018

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Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia

8 July 2018

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

8 July 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

8 July 2018

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Relationship between plasma lipids and palmitoyl-CoA hydrolase and synthetase activities with peroxisomal proliferation in rats treated with fibrates.

8 July 2018

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https://api.crossref.org/works/10.1038%2FSJ.BJP.0706260

Effects of atorvastatin on the intracellular stability and secretion of apolipoprotein B in HepG2 cells

21 January 2018

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Lack of hypotriglyceridemic effect of gemfibrozil as a consequence of age-related changes in rat liver PPARalpha

21 January 2018

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Atorvastatin increases hepatic fatty acid beta-oxidation in sucrose-fed rats: comparison with an MTP inhibitor

25 October 2018

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Avasimibe and atorvastatin synergistically reduce cholesteryl ester content in THP-1 macrophages

25 October 2018

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Atorvastatin treatment induced peroxisome proliferator-activated receptor alpha expression and decreased plasma nonesterified fatty acids and liver triglyceride in fructose-fed rats

25 October 2018

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High doses of atorvastatin and simvastatin induce key enzymes involved in VLDL production

25 October 2018

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Characterization of the human PPARalpha promoter: identification of a functional nuclear receptor response element

25 October 2018

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Leptin resistance during aging is independent of fat mass

25 October 2018

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Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.

25 October 2018

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Lipid-lowering activity of atorvastatin and lovastatin in rodent species: triglyceride-lowering in rats correlates with efficacy in LDL animal models

25 October 2018

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12 December 2020

Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements

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12 December 2020

Expression of the Peroxisome Proliferator-activated Receptor Gene Is Stimulated by Stress and Follows a Diurnal Rhythm

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12 December 2020

Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in pri

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12 December 2020

Sexual dimorphism in lipid metabolic phenotype associated with old age in Sprague–Dawley rats

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12 December 2020

Dynamic alterations occur in the levels and composition of transcription factor AP-1 complexes after seizure

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12 December 2020

Characterization of the Human PPARα Promoter: Identification of a Functional Nuclear Receptor Response Element

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0706260

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912134%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912134%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference