Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses (Q35049821)

6 August 2017

title

Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses (English)

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6 August 2017

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10

Kate E Broderick

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6 August 2017

17

David B Weiner

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6 August 2017

Mark L Bagarazzi

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6 August 2017

Jian Yan

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Matthew P Morrow

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Xuefei Shen

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R Lamar Parker

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Jessica C Lee

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Mary Giffear

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Panyupa Pankhong

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Amir S Khan

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6 August 2017

Christine Knott

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6 August 2017

Feng Lin

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6 August 2017

Jean D Boyer

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Ruxandra Draghia-Akli

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C Jo White

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J Joseph Kim

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Niranjan Y Sardesai

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6 August 2017

language of work or name

English

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publication date

1 October 2012

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Science Translational Medicine

6 August 2017

published in

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6 August 2017

volume

4

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6 August 2017

issue

155

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6 August 2017

page(s)

155ra138

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Therapeutic intervention in cancer and chronic viral infections: antibody mediated manipulation of PD-1/PD-L1 interaction

6 August 2017

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8 July 2018

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Diminished IFN-gamma and IL-10 and elevated Foxp3 mRNA expression in the cervix are associated with CIN 2 or 3.

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Cellular immunity induced by a novel HPV18 DNA vaccine encoding an E6/E7 fusion consensus protein in mice and rhesus macaques

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation

8 July 2018

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8 July 2018

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CD4(+)CD25hi regulatory T-cell frequency correlates with persistence of human papillomavirus type 16 and T helper cell responses in patients with cervical intraepithelial neoplasia

21 January 2018

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21 January 2018

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21 January 2018

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Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX adjuvant in women with cervical intraepithelial neoplasia

21 January 2018

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25 October 2018

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Regression of cervical intraepithelial neoplasia and loss of human papillomavirus (HPV) infection is associated with cell-mediated immune responses to an HPV type 16 E7 peptide

25 October 2018

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25 October 2018

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Mutational analysis of HPV-18 E6 identifies domains required for p53 degradation in vitro, abolition of p53 transactivation in vivo and immortalisation of primary BMK cells.

25 October 2018

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Enhancement of human papillomavirus (HPV) type 16 E6 and E7-specific T-cell immunity in healthy volunteers through vaccination with TA-CIN, an HPV16 L2E7E6 fusion protein vaccine

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10.1126/SCITRANSLMED.3004414

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference