Ezogabine: a new angle on potassium gates (Q35052160)

6 August 2017

title

Ezogabine: a new angle on potassium gates (English)

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6 August 2017

Edward Faught

1

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6 August 2017

language of work or name

English

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publication date

1 May 2011

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6 August 2017

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6 August 2017

volume

11

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6 August 2017

issue

3

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6 August 2017

page(s)

75-78

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Isoform-specific prolongation of Kv7 (KCNQ) potassium channel opening mediated by new molecular determinants for drug-channel interactions

6 August 2017

cites work

1 reference

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Placebo-corrected efficacy of modern antiepileptic drugs for refractory epilepsy: systematic review and meta-analysis

8 July 2018

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Neural KCNQ (Kv7) channels

8 July 2018

1 reference

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Potassium channels: brief overview and implications in epilepsy

8 July 2018

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Nervous system KV7 disorders: breakdown of a subthreshold brake

8 July 2018

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Retigabine: has the orphan found a home?

8 July 2018

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Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures

8 July 2018

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Ion channel defects in idiopathic epilepsies

8 July 2018

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Lack of pharmacokinetic interaction between retigabine and phenobarbitone at steady-state in healthy subjects

8 July 2018

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Multiple-dose, linear, dose-proportional pharmacokinetics of retigabine in healthy volunteers

8 July 2018

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The effects of D-23129, a new experimental anticonvulsant drug, on neurotransmitter amino acids in the rat hippocampus in vitro.

8 July 2018

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D-23129: a potent anticonvulsant in the amygdala kindling model of complex partial seizures

8 July 2018

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The American Urological Association symptom index for benign prostatic hyperplasia. The Measurement Committee of the American Urological Association

8 July 2018

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Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy.

8 July 2018

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Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy.

25 October 2018

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Refinement of the binding site and mode of action of the anticonvulsant Retigabine on KCNQ K+ channels.

25 October 2018

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Isobolographic characterization of interactions of retigabine with carbamazepine, lamotrigine, and valproate in the mouse maximal electroshock-induced seizure model.

25 October 2018

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KCNQ2 and KCNQ3 mutations contribute to different idiopathic epilepsy syndromes.

25 October 2018

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Retigabine: bending potassium channels to our will

25 October 2018

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The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate

25 October 2018

1 reference

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Urodynamic effects of the K+ channel (KCNQ) opener retigabine in freely moving, conscious rats

25 October 2018

1 reference

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The anticonvulsant retigabine potently suppresses epileptiform discharges in the low Ca ++ and low Mg++ model in the hippocampal slice preparation.

25 October 2018

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AWD 140-190: a new anticonvulsant with a very good margin of safety.

25 October 2018

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D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures.

25 October 2018

1 reference

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10.5698/1535-7511-11.3.75

25 October 2018

Identifiers

DOI

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6 August 2017

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6 August 2017

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