(-)-gossypol inhibits growth and promotes apoptosis of human head and neck squamous cell carcinoma in vivo (Q35052194)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16611409%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

(-)-gossypol inhibits growth and promotes apoptosis of human head and neck squamous cell carcinoma in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16611409%20AND%20SRC:MED&resulttype=core&format=json

head and neck squamous cell carcinoma

19 January 2020

main subject

(-)-gossypol

0 references

1 reference

8

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19 January 2020

author name string

Keith G Wolter

1

1 reference

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19 January 2020

Steven J Wang

2

1 reference

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19 January 2020

Bradley S Henson

3

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19 January 2020

Shaomeng Wang

4

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19 January 2020

Kent A Griffith

5

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19 January 2020

Bhavna Kumar

6

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19 January 2020

Jianyong Chen

7

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19 January 2020

Carol R Bradford

9

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19 January 2020

Nisha J D'Silva

10

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19 January 2020

publication date

1 March 2006

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19 January 2020

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19 January 2020

volume

8

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19 January 2020

issue

3

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19 January 2020

page(s)

163-172

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Promoting apoptosis as a strategy for cancer drug discovery

19 January 2020

cites work

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In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells.

8 July 2018

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Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45

8 July 2018

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8 July 2018

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8 July 2018

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Oblimersen Bcl-2 antisense: facilitating apoptosis in anticancer treatment

8 July 2018

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Expression of Bcl-2 family proteins in advanced laryngeal squamous cell carcinoma: correlation with response to chemotherapy and organ preservation

8 July 2018

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Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

8 July 2018

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Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

8 July 2018

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Cytotoxicity of gossypol enantiomers and its quinone metabolite gossypolone in melanoma cell lines.

8 July 2018

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Gossypol inhibition of mitosis, cyclin D1 and Rb protein in human mammary cancer cells and cyclin-D1 transfected human fibrosarcoma cells

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL.

8 July 2018

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25 October 2018

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Rap1A and rap1B ras-family proteins are prominently expressed in the nucleus of squamous carcinomas: nuclear translocation of GTP-bound active form.

25 October 2018

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25 October 2018

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25 October 2018

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25 October 2018

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25 October 2018

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25 October 2018

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12 December 2020

Rap1, a small GTP-binding protein is upregulated during arrest of proliferation in human keratinocytes

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12 December 2020

Bcl-xL is expressed in ovarian carcinoma and modulates chemotherapy-induced apoptosis

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12 December 2020

Taxol and estramustine-induced modulation of human prostate cancer cell apoptosis via alteration in bcl-xL and bak expression

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12 December 2020

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma

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12 December 2020

Cytotoxic effect of gossypol on colon carcinoma cells

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12 December 2020

Identifiers

DOI

10.1593/NEO.05691

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16611409%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16611409%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

16611409

1 reference