Increased axonal mitochondrial mobility does not slow amyotrophic lateral sclerosis (ALS)-like disease in mutant SOD1 mice (Q35067857)

6 August 2017

title

Increased axonal mitochondrial mobility does not slow amyotrophic lateral sclerosis (ALS)-like disease in mutant SOD1 mice (English)

1 reference

amyotrophic lateral sclerosis

6 August 2017

main subject

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author name string

Yi-Bing Zhu

series ordinal

1

1 reference

6 August 2017

Zu-Hang Sheng

series ordinal

2

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6 August 2017

language of work or name

English

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publication date

25 April 2011

1 reference

Journal of Biological Chemistry

6 August 2017

published in

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6 August 2017

volume

286

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6 August 2017

issue

26

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6 August 2017

page(s)

23432-23440

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Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease.

6 August 2017

cites work

1 reference

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Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

8 July 2018

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Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS

8 July 2018

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Axonal transport defects in neurodegenerative diseases

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Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities

8 July 2018

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Moving or stopping mitochondria: Miro as a traffic cop by sensing calcium

8 July 2018

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The Psi(m) depolarization that accompanies mitochondrial Ca2+ uptake is greater in mutant SOD1 than in wild-type mouse motor terminals.

8 July 2018

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The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility

8 July 2018

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Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3

8 July 2018

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Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death

8 July 2018

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Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria.

8 July 2018

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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

8 July 2018

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Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation

8 July 2018

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Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content

8 July 2018

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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

8 July 2018

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Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex

8 July 2018

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Molecular biology of amyotrophic lateral sclerosis: insights from genetics

8 July 2018

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Onset and progression in inherited ALS determined by motor neurons and microglia

8 July 2018

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The axonal transport of mitochondria.

8 July 2018

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A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice

8 July 2018

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8 July 2018

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ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes

8 July 2018

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8 July 2018

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From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

8 July 2018

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Visualization of defective mitochondrial function in skeletal muscle fibers of patients with sporadic amyotrophic lateral sclerosis

8 July 2018

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Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

8 July 2018

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Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

8 July 2018

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

8 July 2018

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8 July 2018

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Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis

8 July 2018

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SAGE analysis of genes differentially expressed in presymptomatic TgSOD1G93A transgenic mice identified cellular processes involved in early stage of ALS pathology

8 July 2018

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Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.

27 September 2018

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Differences in mitochondrial movement and morphology in young and mature primary cortical neurons in culture

27 September 2018

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Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice

27 September 2018

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Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice.

27 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123107

Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

27 September 2018

1 reference

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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123107

Up‐regulation of mitochondrial uncoupling protein 3 reveals an early muscular metabolic defect in amyotrophic lateral sclerosis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123107

Mutations in dynein link motor neuron degeneration to defects in retrograde transport

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123107

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123107

Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123107

Selective impairment of fast anterograde axonal transport in the peripheral nerves of asymptomatic transgenic mice with a G93A mutant SOD1 gene

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123107

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.237818

Mutant superoxide dismutase disrupts cytoplasmic dynein in motor neurons

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.237818

Impairment of fast axonal transport in the proximal axons of anterior horn neurons in amyotrophic lateral sclerosis

21 January 2018

1 reference

12 December 2020

Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

1 reference

12 December 2020

A dynein mutation attenuates motor neuron degeneration in SOD1(G93A) mice

1 reference

12 December 2020

Mitochondrial alterations in the spinal cord of patients with sporadic amyotrophic lateral sclerosis

1 reference

12 December 2020

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

1 reference

12 December 2020

Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.237818

1 reference

6 August 2017

1 reference

6 August 2017

1 reference