TP53 in hematological cancer: low incidence of mutations with significant clinical relevance (Q35078753)

6 August 2017

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title

TP53 in hematological cancer: low incidence of mutations with significant clinical relevance (English)

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6 August 2017

2

Varda Rotter

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6 August 2017

Shoshana Peller

1

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6 August 2017

1 March 2003

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6 August 2017

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6 August 2017

21

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6 August 2017

3

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6 August 2017

277-284

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Significance of p53 mutations in patients with chronic lymphocytic leukemia: a sequential study of 30 patients

6 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Alterations of P53 and RB genes and the evolution of the accelerated phase of chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

TP53 family members and human cancers

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Translocations involving the short arm of chromosome 17 in chronic B-lymphoid disorders: frequent occurrence of dicentric rearrangements and possible association with adverse outcome

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Apoptosis of tumoral and nontumoral lymphoid cells is induced by both mdm2 and p53 antisense oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor progno

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Multiple cell cycle regulator alterations in Richter's transformation of chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Significantly different bcl-2 expression profiles in gastric and non-gastric primary extranodal high-grade B-cell lymphomas

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https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Karyotypic abnormalities associated with haemopoietic lineage switching are not linked with mutations to p53

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https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

p53 alterations in human leukemia-lymphoma cell lines: in vitroartifact or prerequisite for cell immortalization?

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Concurrent disruption of cell cycle associated genes in mantle cell lymphoma: a genotypic and phenotypic study of cyclin D1, p16, p15, p53 and pRb.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Concurrent disruption of p16INK4a and the ARF-p53 pathway predicts poor prognosis in aggressive non-Hodgkin's lymphoma.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

p53 abnormalities in splenic lymphoma with villous lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Structure and function of the p53 tumor suppressor gene: clues for rational cancer therapeutic strategies

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Mdm2 promotes the rapid degradation of p53

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https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

A Multicentric Study of 41 Cases of B-Prolymphocytic Leukemia: Two Evolutive Forms: The Groupe Français d'Hématologie Cellulaire

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Cellular stress response and apoptosis in cancer therapy.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Mutations of the p53 gene as a prognostic factor in aggressive B-cell lymphoma.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Tumor-suppressor p53: implications for tumor development and prognosis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

p53 mutations in hairy cell leukemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Tumor suppressor genes in normal and malignant hematopoiesis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Simultaneous detection of BCL-2 protein, trisomy 12, retinoblastoma and P53 monoallelic gene deletions in B-cell chronic lymphocytic leukemia by fluorescence in situ hybridization (FISH): relation to disease status

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Functional analysis of the p53 protein in AIDS-related non-Hodgkin's lymphomas and polymorphic lymphoproliferations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Potential role for wild-type p53 in leukemias with MLL gene translocations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Aberrations of the p53 pathway components p53, MDM2 and CDKN2A appear independent in diffuse large B cell lymphoma

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Prognostic value of p53 gene mutations and the product expression in de novo acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

RAS, FMS and p53 mutations and poor clinical outcome in myelodysplasias: a 10-year follow-up.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Mitochondrial membrane sensitivity to depolarization in acute myeloblastic leukemia is associated with spontaneous in vitro apoptosis, wild-type TP53, and vicinal thiol/disulfide status

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Intraclonal heterogeneity in the in vitro daunorubicin-induced apoptosis in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Clinical implications of p53: effect on prognosis, tumor progression and chemotherapy response

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Molecular alterations in the TP53 gene of peripheral blood cells of patients with chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Expression of p53 protein in T- and natural killer-cell lymphomas is associated with some clinicopathologic entities but rarely related to p53 mutations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

The clinical significance of mutations of the P53 tumour suppressor gene in haematological malignancies

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

P53 gene mutation in a T-acute lymphoblastic leukemia cell line (loucy) with t(16:20) and 5q- chromosomal aberrations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Pooled analysis of p53 mutations in hematological malignancies.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

p53 Mutations in nasal natural killer/T-cell lymphoma from Mexico: association with large cell morphology and advanced disease

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

p14ARF nuclear overexpression in aggressive B-cell lymphomas is a sensor of malfunction of the common tumor suppressor pathways

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

TP53 deletions but not trisomy 12 are adverse in B-cell lymphoproliferative disorders

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Genetic features of B-cell chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Oncogenic aberrations in the p53 pathway are associated with a high S phase fraction and poor patient survival in B-cell Non-Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Incidence and prognostic significance of MDM2 oncoprotein overexpression in relapsed childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10190

7 January 2021

Identifiers

DOI

10.1002/HUMU.10190

1 reference

6 August 2017

1 reference

PubMed ID

12619113