Concurrent disruption of p16INK4a and the ARF-p53 pathway predicts poor prognosis in aggressive non-Hodgkin's lymphoma. (Q52541204)

3 May 2018

title

Concurrent disruption of p16INK4a and the ARF-p53 pathway predicts poor prognosis in aggressive non-Hodgkin's lymphoma. (English)

1 reference

3 May 2018

author name string

Grønbaek K

1

1 reference

3 May 2018

de Nully Brown P

2

1 reference

3 May 2018

Møller MB

3

1 reference

3 May 2018

Nedergaard T

4

1 reference

3 May 2018

Ralfkiaer E

5

1 reference

3 May 2018

Møller P

6

1 reference

3 May 2018

Zeuthen J

7

1 reference

3 May 2018

Guldberg P

8

1 reference

3 May 2018

publication date

1 October 2000

1 reference

3 May 2018

published in

Leukemia

1 reference

3 May 2018

volume

14

1 reference

3 May 2018

issue

10

1 reference

3 May 2018

page(s)

1727-1735

1 reference

3 May 2018

A predictive model for aggressive non-Hodgkin's lymphoma. The International Non-Hodgkin's Lymphoma Prognostic Factors Project

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

The cellular and molecular heterogeneity of the aggressive non-Hodgkin's lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Loss of p16/INK4A protein expression in non-Hodgkin's lymphomas is a frequent finding associated with tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Mutations of the p53 gene as a prognostic factor in aggressive B-cell lymphoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Aberrations of the p53 pathway components p53, MDM2 and CDKN2A appear independent in diffuse large B cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Deletions and rearrangements of cyclin-dependent kinase 4 inhibitor gene p16 are associated with poor prognosis in B cell non-Hodgkin's lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

1 reference

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

E1A signaling to p53 involves the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Selective deletion of exon 1 beta of the p19ARF gene in metastatic melanoma cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Concurrent disruption of cell cycle associated genes in mantle cell lymphoma: a genotypic and phenotypic study of cyclin D1, p16, p15, p53 and pRb.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Germline p16 mutations in familial melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Detection of mutations in GC-rich DNA by bisulphite denaturing gradient gel electrophoresis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Use of denaturing gradient gel electrophoresis to study conformational transitions in nucleic acids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Nonparametric Estimation from Incomplete Observations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

The human protein p19ARF is not detected in hemopoietic human cell lines that abundantly express the alternative beta transcript of the p16INK4a/MTS1 gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Inactivations of p16INK4a-alpha, p16INK4a-beta and p15INK4b genes in 2',3'-dideoxycytidine- and 1,3-butadiene-induced murine lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Deletions of the INK4A gene in superficial bladder tumors. Association with recurrence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401901

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2401901

1 reference

3 May 2018

Dimensions Publication ID

1035052121

0 references

1 reference

3 May 2018