The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells (Q35083432)

6 August 2017

The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells (English)

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6 August 2017

13

Miho Iijima

1 reference

6 August 2017

Zhongyan Zhang

1

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6 August 2017

Nobunao Wakabayashi

2

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6 August 2017

Junko Wakabayashi

3

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6 August 2017

Yasushi Tamura

4

1 reference

6 August 2017

Woo-Jin Song

5

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6 August 2017

Sam Sereda

6

1 reference

6 August 2017

Pascaline Clerc

7

1 reference

6 August 2017

Brian M Polster

8

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6 August 2017

Susan M Aja

9

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6 August 2017

Mikhail V Pletnikov

10

1 reference

6 August 2017

Thomas W Kensler

11

1 reference

6 August 2017

Orian S Shirihai

12

1 reference

6 August 2017

Mehboob A Hussain

14

1 reference

6 August 2017

Hiromi Sesaki

15

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6 August 2017

5 May 2011

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Molecular Biology of the Cell

6 August 2017

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6 August 2017

22

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6 August 2017

13

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6 August 2017

2235-2245

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describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3128526/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Mitochondrial fission and fusion

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Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

8 July 2018

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8 July 2018

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The pathophysiology of mitochondrial disease as modeled in the mouse

8 July 2018

1 reference

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Mitochondrial networking protects beta-cells from nutrient-induced apoptosis.

8 July 2018

1 reference

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Mitochondrial fusion and division: Regulation and role in cell viability

8 July 2018

1 reference

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Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion

8 July 2018

1 reference

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Positioning mitochondrial plasticity within cellular signaling cascades.

8 July 2018

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The C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicals

8 July 2018

1 reference

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Molecular machinery of mitochondrial fusion and fission

8 July 2018

1 reference

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A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility

8 July 2018

1 reference

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Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

8 July 2018

1 reference

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Regulation of mitochondrial fusion and division

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Impaired metabolism-secretion coupling in pancreatic beta-cells: role of determinants of mitochondrial ATP production.

8 July 2018

1 reference

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Detection of mutations in mtDNA.

8 July 2018

1 reference

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The machines that divide and fuse mitochondria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Islet beta cell failure in type 2 diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mitochondria: dynamic organelles in disease, aging, and development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Glucose-sensing mechanisms in pancreatic beta-cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Disruption of fusion results in mitochondrial heterogeneity and dysfunction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mitochondrial dysfunction and type 2 diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

OPA1 requires mitofusin 1 to promote mitochondrial fusion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mitochondrial morphology is dynamic and varied

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mitochondrial factors in the pathogenesis of diabetes: a hypothesis for treatment.

8 July 2018

1 reference

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Mitochondrial function in normal and diabetic beta-cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mitochondrial diseases in man and mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Lack of cytochrome c in mouse fibroblasts disrupts assembly/stability of respiratory complexes I and IV.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Augmented beta cell loss and mitochondrial abnormalities in sucrose-fed GK rats

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

-Cell Mitochondria Exhibit Membrane Potential Heterogeneity That Can Be Altered by Stimulatory or Toxic Fuel Levels

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128526

Mitochondrial damages and the regulation of insulin secretion

8 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21551073

12 December 2020

inferred from PubMed ID database lookup

Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21551073

12 December 2020

inferred from PubMed ID database lookup

Enlargement of the lateral ventricles in mutant DISC1 transgenic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21551073

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1091/MBC.E10-12-0933

1 reference

6 August 2017

1 reference

6 August 2017

1 reference