The anti-tumor activity of a neutralizing nanobody targeting leptin receptor in a mouse model of melanoma. (Q35108291)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24587106%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

The anti-tumor activity of a neutralizing nanobody targeting leptin receptor in a mouse model of melanoma (English)

1 reference

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9 March 2020

3

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9 March 2020

author name string

Travis McMurphy

1

1 reference

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9 March 2020

Run Xiao

2

1 reference

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9 March 2020

Andrew Slater

4

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9 March 2020

Lennart Zabeau

5

1 reference

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9 March 2020

Jan Tavernier

6

1 reference

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9 March 2020

Lei Cao

7

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9 March 2020

language of work or name

English

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publication date

28 February 2014

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9 March 2020

1 reference

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9 March 2020

volume

9

1 reference

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9 March 2020

issue

2

1 reference

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9 March 2020

page(s)

e89895

1 reference

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Creative Commons Attribution 4.0 International

9 March 2020

copyright license

start time

28 February 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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9 July 2018

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9 July 2018

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Obesity promotes melanoma tumor growth: role of leptin

9 July 2018

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Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer

9 July 2018

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Leptin-dependent control of glucose balance and locomotor activity by POMC neurons.

9 July 2018

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9 July 2018

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9 July 2018

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Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

9 July 2018

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Mechanisms of leptin action and leptin resistance

9 July 2018

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Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice

9 July 2018

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Soluble receptor inhibits leptin transport

9 July 2018

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Central nervous system control of food intake and body weight

9 July 2018

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Leptin receptor expression and cell signaling in breast cancer.

9 July 2018

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Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis

9 July 2018

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Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis

9 July 2018

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9 July 2018

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Leptin increase in multiple sclerosis associates with reduced number of CD4(+)CD25+ regulatory T cells

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Characterizaton of short isoforms of the leptin receptor in rat cerebral microvessels and of brain uptake of leptin in mouse models of obesity

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Human leptin: from an adipocyte hormone to an endocrine mediator

9 July 2018

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9 July 2018

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Identification and expression cloning of a leptin receptor, OB-R

9 July 2018

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9 July 2018

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Positional cloning of the mouse obese gene and its human homologue

9 July 2018

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Adiposity, mediating biomarkers and risk of colon cancer in the European prospective investigation into cancer and nutrition study

9 July 2018

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Selection of non-competitive leptin antagonists using a random nanobody-based approach.

27 September 2018

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Hyperinsulinemia precedes insulin resistance in mice lacking pancreatic beta-cell leptin signaling

27 September 2018

1 reference

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Melanoma risk in association with serum leptin levels and lifestyle parameters: a case-control study.

27 September 2018

1 reference

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The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

27 September 2018

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27 September 2018

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Formatted anti-tumor necrosis factor alpha VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen-induced arthritis.

27 September 2018

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Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis

27 September 2018

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Circulating soluble leptin receptor, leptin, and insulin resistance before and after weight loss in obese children

27 September 2018

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Astrocytes in the arcuate nucleus and median eminence that take up a fluorescent dye from the circulation express leptin receptors and neuropeptide Y Y1 receptors

27 September 2018

1 reference

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Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids, and leptin: observational and interventional studies in humans

27 September 2018

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Expression of leptin receptor isoforms in rat brain microvessels.

27 September 2018

1 reference

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Soluble Leptin Receptor Represents the Main Leptin Binding Activity in Human Blood

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0089895

Decreased transport of leptin across the blood-brain barrier in rats lacking the short form of the leptin receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24587106

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential accessibility of circulating leptin to individual hypothalamic sites

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24587106

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A neutralizing leptin receptor antibody mitigates hypertrophy and hemodynamic dysfunction in the postinfarcted rat heart

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24587106

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0089895

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24587106%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24587106%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24587106%20AND%20SRC:MED&resulttype=core&format=json