RPA antagonizes microhomology-mediated repair of DNA double-strand breaks (Q35114605)

6 August 2017

title

RPA antagonizes microhomology-mediated repair of DNA double-strand breaks (English)

1 reference

6 August 2017

Sarah K Deng

1

1 reference

6 August 2017

Bryan Gibb

2

1 reference

6 August 2017

Mariana Justino de Almeida

3

1 reference

6 August 2017

Eric C Greene

4

1 reference

6 August 2017

Lorraine S Symington

5

1 reference

6 August 2017

publication date

9 March 2014

1 reference

Nature Structural & Molecular Biology

6 August 2017

published in

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6 August 2017

volume

21

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6 August 2017

issue

4

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6 August 2017

page(s)

405-412

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describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3980576/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nsmb.2786

0 references

cites work

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RPA coordinates DNA end resection and prevents formation of DNA hairpins

9 July 2018

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Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

9 July 2018

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Microhomology directs diverse DNA break repair pathways and chromosomal translocations

9 July 2018

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Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks

9 July 2018

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Cyclin-dependent kinase-dependent phosphorylation of Lif1 and Sae2 controls imprecise nonhomologous end joining accompanied by double-strand break resection

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Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.

9 July 2018

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9 July 2018

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9 July 2018

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DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

9 July 2018

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9 July 2018

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CtIP promotes microhomology-mediated alternative end joining during class-switch recombination

9 July 2018

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9 July 2018

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Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA.

9 July 2018

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Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks

9 July 2018

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Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2

9 July 2018

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Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targeting

9 July 2018

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The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

9 July 2018

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DNA end resection: many nucleases make light work

9 July 2018

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DNA helicases Sgs1 and BLM promote DNA double-strand break resection

9 July 2018

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9 July 2018

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9 July 2018

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Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

9 July 2018

1 reference

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Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends

9 July 2018

1 reference

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9 July 2018

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Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks

9 July 2018

1 reference

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Human CtIP promotes DNA end resection

9 July 2018

1 reference

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Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Microhomology-mediated end joining in fission yeast is repressed by pku70 and relies on genes involved in homologous recombination

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

A mechanism of palindromic gene amplification in Saccharomyces cerevisiae

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

DNA ligase III as a candidate component of backup pathways of nonhomologous end joining

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Rejoining of DNA double-strand breaks as a function of overhang length

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Gene targeting in yeast is initiated by two independent strand invasions.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

The Recombination-deficient Mutant RPA (rfa1-t11) Is Displaced Slowly from Single-stranded DNA by Rad51 Protein

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Replication protein A is required for meiotic recombination in Saccharomyces cerevisiae.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

The yeast recombinational repair protein Rad59 interacts with Rad52 and stimulates single-strand annealing

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

An allele of RFA1 suppresses RAD52-dependent double-strand break repair in Saccharomyces cerevisiae

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

DNA annealing by RAD52 protein is stimulated by specific interaction with the complex of replication protein A and single-stranded DNA

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

DNA strand annealing is promoted by the yeast Rad52 protein

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

A mutation in the gene encoding the Saccharomyces cerevisiae single-stranded DNA-binding protein Rfa1 stimulates a RAD52-independent pathway for direct-repeat recombination

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980576

DNA Curtains for High-Throughput Single-Molecule Optical Imaging

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2786

The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24608368

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2786

1 reference

6 August 2017

1 reference

6 August 2017

1 reference