Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model (Q35130805)

6 August 2017

Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model (English)

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6 August 2017

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Xingjun Fan

1

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6 August 2017

Lixing W Reneker

2

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6 August 2017

Mark E Obrenovich

3

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6 August 2017

Christopher Strauch

4

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6 August 2017

Rongzhu Cheng

5

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6 August 2017

Simon M Jarvis

6

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6 August 2017

Beryl J Ortwerth

7

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6 August 2017

Vincent M Monnier

8

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6 August 2017

language of work or name

English

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publication date

30 October 2006

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6 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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6 August 2017

103

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6 August 2017

16912-16917

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6 August 2017

45

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Chick delta1-crystallin enhancer influences mouse alphaA-crystallin promoter activity in transgenic mice.

6 August 2017

1 reference

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Structure elucidation of a novel yellow chromophore from human lens protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

Regulation of the human vitamin C transporters expressed in COS-1 cells by protein kinase C [corrected]

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

Identification and quantification of major maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

Vitamin C transport systems of mammalian cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

Decrease in vitamin C concentration in human lenses during cataract progression.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

Quantitating cataract and nuclear brunescence, the Harvard and LOCS systems.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

The chaperone activity of bovine alpha crystallin. Interaction with other lens crystallins in native and denatured states.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

The role of ascorbic acid in senile cataract

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

Glutathione and its function in the lens--an overview

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

Reaction of ascorbate with lysine and protein under autoxidizing conditions: formation of N epsilon-(carboxymethyl)lysine by reaction between lysine and products of autoxidation of ascorbate

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

A possible role for vitamins C and E in cataract prevention

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

Historical perspective of the Maillard reaction in food science

13 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0605101103

Vitamin C Metabolomic Mapping in the Lens with 6-Deoxy-6-fluoro-ascorbic Acid and High-Resolution19F-NMR Spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0605101103

6-Bromo-6-deoxy-L-ascorbic acid: an ascorbate analog specific for Na+-dependent vitamin C transporter but not glucose transporter pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0605101103

Structure and mechanism of formation of human lens fluorophore LM-1. Relationship to vesperlysine A and the advanced Maillard reaction in aging, diabetes, and cataractogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0605101103

Lens autofluorescence and light scatter in relation to the lens opacities classification system, LOCS III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0605101103

Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0605101103

Human lens coloration and aging. Evidence for crystallin modification by the major ultraviolet filter, 3-hydroxy-kynurenine O-beta-D-glucoside.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0605101103

Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0605101103

Aging affects oxidative state in hippocampus, hypothalamus and adrenal glands of Wistar rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0605101103

Vitamin C transport systems of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0605101103

Protective effect of ascorbate against oxidative stress in the mouse lens.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

LC-MS display of the total modified amino acids in cataract lens proteins and in lens proteins glycated by ascorbic acid in vitro

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636553

Ascorbic acid mediated alteration of alpha-crystallin secondary structure

16 November 2018

1 reference

12 December 2020

Validation of a micromethod for determining oxidized and reduced vitamin C in plasma by HPLC-fluorescence

1 reference

12 December 2020

Long-term vitamin C supplement use and prevalence of early age-related lens opacities

1 reference

12 December 2020

Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: is there oxidative stress in uremia?

1 reference

12 December 2020

A transgenic animal model of osmotic cataract. Part 1: over-expression of bovine Na+/myo-inositol cotransporter in lens fibers

1 reference

12 December 2020

Relative suppression of the sodium-dependent Vitamin C transport in mouse versus human lens epithelial cells

1 reference

12 December 2020

Age-dependent accumulation of N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)hydroxylysine in human skin collagen

1 reference

12 December 2020

Role of glycation in modification of lens crystallins in diabetic and nondiabetic senile cataracts

1 reference

12 December 2020

The glycation and cross-linking of isolated lens crystallins by ascorbic acid

1 reference

12 December 2020

Ascorbic acid in the brain

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0605101103

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6 August 2017

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6 August 2017

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