The Wnt pathway, cell-cycle activation and beta-amyloid: novel therapeutic strategies in Alzheimer's disease? (Q35136322)

6 August 2017

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title

The Wnt pathway, cell-cycle activation and beta-amyloid: novel therapeutic strategies in Alzheimer's disease? (English)

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6 August 2017

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Maria Angela Sortino

6

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ORCID Public Data File 2021

author name string

Andrea Caricasole

1

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6 August 2017

Agata Copani

2

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6 August 2017

Alessandra Caruso

3

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6 August 2017

Filippo Caraci

4

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6 August 2017

Luisa Iacovelli

5

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6 August 2017

Georg C Terstappen

7

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6 August 2017

Ferdinando Nicoletti

8

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6 August 2017

language of work or name

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1 May 2003

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Trends in Pharmacological Sciences

6 August 2017

published in

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6 August 2017

volume

24

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6 August 2017

issue

5

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6 August 2017

page(s)

233-238

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Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Re-entry into the cell cycle: a mechanism for neurodegeneration in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Mitotic signaling by beta-amyloid causes neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Erratic expression of DNA polymerases by beta-amyloid causes neuronal death.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

DNA replication precedes neuronal cell death in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Amyloid beta peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

AbetaPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Wnt signaling function in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Wnt signaling involvement in beta-amyloid-dependent neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Signal transduction by the Wnt family of ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Involvement of DNA polymerase beta in DNA replication and mutagenic consequences

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Mechanisms of neuronal death in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Beta-catenin: a key mediator of Wnt signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Depolarization drives beta-Catenin into neuronal spines promoting changes in synaptic structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Does insulin dysfunction play a role in Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Genetic variability in the insulin signalling pathway may contribute to the risk of late onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Regulation of cerebral cortical size by control of cell cycle exit in neural precursors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Effect of the Alzheimer amyloid fragment Abeta(25-35) on Akt/PKB kinase and survival of PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Beta-amyloid-induced synthesis of the ganglioside GD3 is a requisite for cell cycle reactivation and apoptosis in neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

The cyanogenic glucoside, prunasin (D-mandelonitrile-beta-D-glucoside), is a novel inhibitor of DNA polymerase beta

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

TGF-beta-receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Alzheimer's disease and estrogen

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Glycogen synthase kinase 3: an emerging therapeutic target

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Anti-mitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

Akt participation in the Wnt signaling pathway through Dishevelled

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900100-7

7 January 2021

10.1016/S0165-6147(03)00100-7

Identifiers

DOI

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6 August 2017

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