FBXW7 acts as an independent prognostic marker and inhibits tumor growth in human osteosarcoma. (Q35138854)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622249%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

FBXW7 acts as an independent prognostic marker and inhibits tumor growth in human osteosarcoma (English)

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28 February 2020

2

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28 February 2020

author name string

Zhanchun Li

1

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28 February 2020

Kongzu Hu

3

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28 February 2020

Gang Wang

4

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28 February 2020

Maoqiang Li

5

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28 February 2020

Jidong Zhang

6

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28 February 2020

Guangqi Cheng

7

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28 February 2020

language of work or name

English

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publication date

22 January 2015

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International Journal of Molecular Sciences

28 February 2020

published in

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28 February 2020

volume

16

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28 February 2020

issue

2

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28 February 2020

page(s)

2294-2306

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Creative Commons Attribution 4.0 International

28 February 2020

copyright license

start time

22 January 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma.

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Retracted: Recombinant Human Adenovirus-p53 Injection Induced Apoptosis in Hepatocellular Carcinoma Cell Lines Mediated by p53-Fbxw7 Pathway, Which Controls c-Myc and Cyclin E

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The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability

13 July 2018

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New molecular insights into osteosarcoma targeted therapy

13 July 2018

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C-Myc overexpression promotes osteosarcoma cell invasion via activation of MEK-ERK pathway

13 July 2018

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Tumor suppressor functions of FBW7 in cancer development and progression

13 July 2018

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The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis

13 July 2018

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Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma

13 July 2018

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Cyclin E1 is amplified and overexpressed in osteosarcoma.

13 July 2018

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SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

13 July 2018

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The epidemiology of osteosarcoma

13 July 2018

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Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: clinical significance

13 July 2018

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FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression

13 July 2018

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c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis

13 July 2018

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hCDC4 variation in osteosarcoma

13 July 2018

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The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

13 July 2018

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The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

13 July 2018

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BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets

13 July 2018

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SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

13 July 2018

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Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

13 July 2018

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Evaluation of Fbxw7 expression and its correlation with the expression of c-Myc, cyclin E and p53 in human hepatocellular carcinoma.

13 July 2018

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Reduced expression of ubiquitin ligase FBXW7 mRNA is associated with poor prognosis in breast cancer patients.

27 September 2018

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p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases.

27 September 2018

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A phosphorylation cascade controls the degradation of active SREBP1.

27 September 2018

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FBXW7/hCDC4 is a general tumor suppressor in human cancer.

27 September 2018

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27 September 2018

Identifiers

DOI

10.3390/IJMS16022294

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25622249%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

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28 February 2020

1 reference

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