Optimizing DC vaccination by combination with oncolytic adenovirus coexpressing IL-12 and GM-CSF. (Q35144428)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21468000%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Optimizing DC vaccination by combination with oncolytic adenovirus coexpressing IL-12 and GM-CSF (English)

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27 January 2020

1 reference

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6

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27 January 2020

author name string

Song-Nan Zhang

1

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27 January 2020

Il-Kyu Choi

2

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27 January 2020

Jing-Hua Huang

3

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27 January 2020

Ji-Young Yoo

4

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27 January 2020

Kyung-Ju Choi

5

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27 January 2020

publication date

5 April 2011

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27 January 2020

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27 January 2020

volume

19

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issue

8

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27 January 2020

page(s)

1558-1568

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Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL.

27 January 2020

cites work

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E1A- and E1B-Double mutant replicating adenovirus elicits enhanced oncolytic and antitumor effects

13 July 2018

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Dendritic cell vaccination

13 July 2018

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DC immunotherapy is highly effective for the inhibition of tumor metastasis or recurrence, although it is not efficient for the eradication of established solid tumors

13 July 2018

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13 July 2018

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Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy

13 July 2018

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13 July 2018

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Reversing tumor immune suppression with intratumoral IL-12: activation of tumor-associated T effector/memory cells, induction of T suppressor apoptosis, and infiltration of CD8+ T effectors.

13 July 2018

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13 July 2018

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Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency

13 July 2018

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Dendritic cells as therapeutic vaccines against cancer

13 July 2018

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Mechanisms and functional significance of tumour-induced dendritic-cell defects

13 July 2018

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Development of gene therapy to target pancreatic cancer

13 July 2018

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Cytokine- and chemokine-based gene therapy for cancer

13 July 2018

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Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming

13 July 2018

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Interleukin-12 and the regulation of innate resistance and adaptive immunity

13 July 2018

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Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6.

13 July 2018

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Reciprocal activating interaction between natural killer cells and dendritic cells

13 July 2018

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Tumor lysate-pulsed dendritic cells can elicit an effective antitumor immune response during early lymphoid recovery

13 July 2018

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13 July 2018

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IL-12 regulates VEGF and MMPs in a murine breast cancer model

13 July 2018

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13 July 2018

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The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis

13 July 2018

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The contribution of vascular endothelial growth factor to the induction of regulatory T-cells in malignant effusions.

27 September 2018

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Synergy between dendritic cells and GM-CSF-secreting tumor cells for the treatment of a murine renal cell carcinoma.

27 September 2018

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Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model.

27 September 2018

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Immunologic and clinical responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients

27 September 2018

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Stat1 deficiency in the host enhances interleukin-12-mediated tumor regression

27 September 2018

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Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect.

27 September 2018

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Oncolytic replication-competent adenovirus suppresses tumor angiogenesis through preserved E1A region.

27 September 2018

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Immunological properties and vaccine efficacy of murine dendritic cells simultaneously expressing melanoma-associated antigen and interleukin-12.

27 September 2018

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Prevention of angiogenesis by naked DNA IL-12 gene transfer: angioprevention by immunogene therapy.

27 September 2018

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Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer

27 September 2018

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A phase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy

27 September 2018

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Mice vaccination with interleukin 12-transduced colon cancer cells potentiates rejection of syngeneic non-organ-related tumor cells.

27 September 2018

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Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149171

Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149171

Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12

16 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149171

Dendritic cell activation by combined exposure to anti-CD40 plus interleukin (IL)-12 and IL-18 efficiently stimulates anti-tumor immunity

16 November 2018

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12 December 2020

Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function

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12 December 2020

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

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12 December 2020

Follow-up evaluation of prostate cancer patients infused with autologous dendritic cells pulsed with PSMA peptides

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12 December 2020

Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production

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12 December 2020

Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells

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12 December 2020

Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12

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12 December 2020

Migration of human dendritic cells after injection in patients with metastatic malignancies

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12 December 2020

Transfection of immature murine bone marrow-derived dendritic cells with the granulocyte-macrophage colony-stimulating factor gene potently enhances their in vivo antigen-presenting capacity

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12 December 2020

Identifiers

DOI

10.1038/MT.2011.29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21468000%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21468000%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

21468000

1 reference