A data-driven, mathematical model of mammalian cell cycle regulation. (Q35168017)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24824602%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

A data-driven, mathematical model of mammalian cell cycle regulation (English)

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18 March 2020

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3

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18 March 2020

author name string

Michael C Weis

series ordinal

1

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18 March 2020

Jayant Avva

series ordinal

2

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18 March 2020

Sree N Sreenath

series ordinal

4

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18 March 2020

language of work or name

English

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publication date

13 May 2014

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18 March 2020

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18 March 2020

volume

9

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18 March 2020

issue

5

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18 March 2020

page(s)

e97130

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Creative Commons Attribution 4.0 International

18 March 2020

copyright license

start time

13 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Specialized roles of the two mitotic cyclins in somatic cells: cyclin A as an activator of M phase-promoting factor

13 July 2018

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A systems biology dynamical model of mammalian G1 cell cycle progression

13 July 2018

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Analysis of a generic model of eukaryotic cell-cycle regulation

13 July 2018

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Linking cell division to cell growth in a spatiotemporal model of the cell cycle

13 July 2018

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Systems-level dissection of the cell-cycle oscillator: bypassing positive feedback produces damped oscillations

13 July 2018

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E2Fs link the control of G1/S and G2/M transcription

13 July 2018

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The ups and downs of modeling the cell cycle

13 July 2018

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Integrative analysis of cell cycle control in budding yeast

13 July 2018

1 reference

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Modelling the fission yeast cell cycle

13 July 2018

1 reference

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13 July 2018

Recycling the Cell Cycle

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Mathematical model of the morphogenesis checkpoint in budding yeast.

13 July 2018

1 reference

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Parameter estimation in biochemical pathways: a comparison of global optimization methods

13 July 2018

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Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.

13 July 2018

1 reference

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Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability

13 July 2018

1 reference

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Testing a mathematical model of the yeast cell cycle

13 July 2018

1 reference

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Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases

13 July 2018

1 reference

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Mitotic kinases as regulators of cell division and its checkpoints

13 July 2018

1 reference

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Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

13 July 2018

1 reference

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On the concentrations of cyclins and cyclin-dependent kinases in extracts of cultured human cells.

13 July 2018

1 reference

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Modeling the fission yeast cell cycle: quantized cycle times in wee1- cdc25Delta mutant cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Kinetic analysis of a molecular model of the budding yeast cell cycle

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

A quantitative analysis of the kinetics of the G(2) DNA damage checkpoint system

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

The INK4 family of cell cycle inhibitors in cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

E2F target genes and cell-cycle checkpoint control

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

The cell-cycle regulated transcription factor B-Myb is phosphorylated by cyclin A/Cdk2 at sites that enhance its transactivation properties

13 July 2018

1 reference

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A theory for controlling cell cycle dynamics using a reversibly binding inhibitor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Mathematical model of the fission yeast cell cycle with checkpoint controls at the G1/S, G2/M and metaphase/anaphase transitions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Modeling the control of DNA replication in fission yeast

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Specific regulation of E2F family members by cyclin-dependent kinases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Phosphorylation and activation of B-Myb by cyclin A-Cdk2.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Cytometry of cyclin proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

An amplified sensitivity arising from covalent modification in biological systems

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Mathematical Analysis of a Model of the Mitotic Clock

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Modeling the cell division cycle: cdc2 and cyclin interactions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Twenty-five years of cell cycle genetics

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Cyclin A potentiates maturation-promoting factor activation in the early Xenopus embryo via inhibition of the tyrosine kinase that phosphorylates cdc2

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Cyclin A- and cyclin B-dependent protein kinases are regulated by different mechanisms in Xenopus egg extracts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Relationship between RNA content and progression of lymphocytes through S phase of cell cycle

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Cubism and the cell cycle: the many faces of the APC/C.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Linking data to models: data regression

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

A simple time delay model for eukaryotic cell cycle

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Systems Biology Toolbox for MATLAB: a computational platform for research in systems biology.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

A model for restriction point control of the mammalian cell cycle.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Bifurcation analysis of the regulatory modules of the mammalian G1/S transition

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Mathematical model of the cell division cycle of fission yeast.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Regulation of the mammalian cell cycle: a model of the G1-to-S transition

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Mathematical model for early development of the sea urchin embryo.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

The kinetic origins of the restriction point in the mammalian cell cycle.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

A mathematical description of regulation of the G1-S transition of the mammalian cell cycle.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

DNA-binding activity of the transcription factor upstream stimulatory factor 1 (USF-1) is regulated by cyclin-dependent phosphorylation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

A model of the G1 phase of the cell cycle incorporating cyclin E/cdk2 complex and retinoblastoma protein.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019653

Flow cytometry study of human cyclin B1 and cyclin E expression in leukemic cell lines: cell cycle kinetics and cell localization

27 September 2018

1 reference

12 December 2020

Growth imbalance and altered expression of cyclins B1, A, E, and D3 in MOLT-4 cells synchronized in the cell cycle by inhibitors of DNA replication

1 reference

12 December 2020

The ratio of RNA to total nucleic acid content as a quantitative measure of unbalanced cell growth

1 reference

12 December 2020

Correlation between cell enlargement and nucleic acid and protein content of HeLa cells in unbalanced growth produced by inhibitors of DNA synthesis

1 reference

12 December 2020

Unbalanced growth and cell death in HeLa S3 cultures treated with DNA synthesis inhibitors

1 reference

12 December 2020

Bistable biochemical switching and the control of the events of the cell cycle*

1 reference

12 December 2020

Cell cycle-dependent usage of transcriptional start sites. A novel mechanism for regulation of cyclin B1

1 reference

12 December 2020

A model for a network of phosphorylation-dephosphorylation cycles displaying the dynamics of dominoes and clocks

1 reference

12 December 2020

Functional capabilities of molecular network components controlling the mammalian G1/S cell cycle phase transition

1 reference

12 December 2020

Cytotoxicity of a factor isolated from human spleen

1 reference

12 December 2020

Recycling the cell cycle: cyclins revisited

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0097130

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24824602%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24824602%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

PubMed publication ID

24824602

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24824602%20AND%20SRC:MED&resulttype=core&format=json