Integrin-dependent pathologies (Q35170443)

6 August 2017

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title

Integrin-dependent pathologies (English)

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6 August 2017

Bernhard Wehrle-Haller

series ordinal

1

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PubMed ID

12845615

6 August 2017

Beat A Imhof

series ordinal

2

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6 August 2017

1 July 2003

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6 August 2017

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6 August 2017

200

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6 August 2017

4

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6 August 2017

481-487

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Assembly and mechanosensory function of focal contacts

6 August 2017

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The inner lives of focal adhesions

21 January 2018

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Integrins: bidirectional, allosteric signaling machines

21 January 2018

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The lamellipodium: where motility begins

21 January 2018

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Actin, microtubules and focal adhesion dynamics during cell migration

21 January 2018

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

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Interplay between Rac and Rho in the control of substrate contact dynamics

21 January 2018

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Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

21 January 2018

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Separation of propulsive and adhesive traction stresses in locomoting keratocytes

21 January 2018

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Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior

21 January 2018

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Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

21 January 2018

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Focal adhesion motility revealed in stationary fibroblasts

21 January 2018

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Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

21 January 2018

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A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

21 January 2018

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Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

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Conformational regulation of integrin structure and function

21 January 2018

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Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

21 January 2018

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Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

21 January 2018

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Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain

21 January 2018

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The phosphotyrosine binding-like domain of talin activates integrins

21 January 2018

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Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration

21 January 2018

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Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins

21 January 2018

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Leukocyte adhesion deficiency II: therapy and genetic defect

21 January 2018

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Genetic analysis of integrin function in man: LAD-1 and other syndromes.

21 January 2018

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A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1.

21 January 2018

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A novel genetic leukocyte adhesion deficiency in subsecond triggering of integrin avidity by endothelial chemokines results in impaired leukocyte arrest on vascular endothelium under shear flow.

21 January 2018

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A novel syndrome of variant leukocyte adhesion deficiency involving defects in adhesion mediated by beta1 and beta2 integrins

21 January 2018

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Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins

21 January 2018

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Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation

21 January 2018

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A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins

21 January 2018

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Glanzmann's thrombasthenia: updated.

21 January 2018

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A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa (alphaIIbbeta3) integrin receptor locked in a high-affinity state and a Glanzmann thrombasthenia-like phenotype

21 January 2018

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Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation

21 January 2018

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A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis.

21 January 2018

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The Pl(A2) polymorphism of integrin beta(3) enhances outside-in signaling and adhesive functions

21 January 2018

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The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing

21 January 2018

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Integrin alpha(IIb)beta(3) signaling in platelet adhesion and aggregation

21 January 2018

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Homozygous alpha6 integrin mutation in junctional epidermolysis bullosa with congenital duodenal atresia.

21 January 2018

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Novel ITGB4 mutations in lethal and nonlethal variants of epidermolysis bullosa with pyloric atresia: missense versus nonsense

21 January 2018

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Mutation analysis and molecular genetics of epidermolysis bullosa

21 January 2018

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Deletion of a cytoplasmic domain of integrin beta4 causes epidermolysis bullosa simplex

21 January 2018

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Autoantibodies to human alpha6 integrin in patients with oral pemphigoid

21 January 2018

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Muscular dystrophies, the cytoskeleton and cell adhesion

21 January 2018

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Mutations in the laminin alpha 2-chain gene (LAMA2) cause merosin-deficient congenital muscular dystrophy

21 January 2018

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Mutations in the integrin alpha7 gene cause congenital myopathy

21 January 2018

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Integrin alpha 7 beta 1 in muscular dystrophy/myopathy of unknown etiology.

21 January 2018

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Absence of integrin alpha 7 causes a novel form of muscular dystrophy

21 January 2018

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Expression of alpha7beta1 integrin splicing variants during skeletal muscle regeneration.

21 January 2018

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Integrin and dystrophin associated adhesion protein complexes during regeneration of shearing-type muscle injury.

21 January 2018

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Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice

21 January 2018

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Integrin activation controls metastasis in human breast cancer

21 January 2018

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Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo.

21 January 2018

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Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

21 January 2018

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

21 January 2018

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A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control

21 January 2018

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The Severe and Moderate Phenotypes of Heritable Mac-1, LFA-1 Deficiency: Their Quantitative Definition and Relation to Leukocyte Dysfunction and Clinical Features

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/PATH.1399

1 reference

6 August 2017

1 reference

PubMed ID

12845615