Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation (Q35170755)

6 August 2017

Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation (English)

1 reference

6 August 2017

Sarah Sertic

1

1 reference

6 August 2017

Sara Pizzi

2

1 reference

6 August 2017

Ross Cloney

3

1 reference

6 August 2017

Alan R Lehmann

4

1 reference

6 August 2017

Federica Marini

5

1 reference

6 August 2017

Paolo Plevani

6

1 reference

6 August 2017

Marco Muzi-Falconi

7

1 reference

6 August 2017

language of work or name

English

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publication date

1 August 2011

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Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

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6 August 2017

108

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6 August 2017

33

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6 August 2017

13647-13652

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Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Checkpoint mechanisms at the intersection between DNA damage and repair

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

The DNA damage response: ten years after

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

DNA nucleotide excision repair-dependent signaling to checkpoint activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Transcription-coupled repair and premature ageing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Unwind and slow down: checkpoint activation by helicase and polymerase uncoupling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Degradation of human exonuclease 1b upon DNA synthesis inhibition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Is hEXO1 a cancer predisposing gene?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Sequential assembly of the nucleotide excision repair factors in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Aberrant mobility phenomena of the DNA repair protein XPA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Molecular mechanism of nucleotide excision repair.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

Coordination of dual incision and repair synthesis in human nucleotide excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

EXO1-A multi-tasking eukaryotic nuclease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

ATR-dependent pathways control hEXO1 stability in response to stalled forks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

From proteases to proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108547108

Clinical impact of ATR checkpoint signalling failure in humans

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158162

27 September 2018

Identifiers

DOI

10.1073/PNAS.1108547108

1 reference

6 August 2017

0 references

1 reference

6 August 2017

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