Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors). (Q35170819)

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9 February 2020

title

Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors) (English)

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9 February 2020

3

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9 February 2020

author name string

Damien S K Samways

series ordinal

1

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9 February 2020

Baljit S Khakh

series ordinal

2

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9 February 2020

Terrance M Egan

series ordinal

4

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9 February 2020

language of work or name

English

0 references

publication date

1 August 2011

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Proceedings of the National Academy of Sciences of the United States of America

9 February 2020

published in

1 reference

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9 February 2020

volume

108

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9 February 2020

issue

33

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9 February 2020

page(s)

13800-13805

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Ion access pathway to the transmembrane pore in P2X receptor channels

9 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells

28 July 2018

1 reference

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A putative extracellular salt bridge at the subunit interface contributes to the ion channel function of the ATP-gated P2X2 receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

New structure enlivens interest in P2X receptors.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

The neural-glial purinergic receptor ensemble in chronic pain states

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Crystal structure of the ATP-gated P2X(4) ion channel in the closed state

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

ATP-gated P2X cation-channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Gating the pore of P2X receptor channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Ivermectin Interaction with transmembrane helices reveals widespread rearrangements during opening of P2X receptor channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Acidic amino acids impart enhanced Ca2+ permeability and flux in two members of the ATP-gated P2X receptor family

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

P2X receptors as cell-surface ATP sensors in health and disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

The carboxyl-terminal region of cyclic nucleotide-modulated channels is a gating ring, not a permeation path

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Refined structure of the nicotinic acetylcholine receptor at 4A resolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Contribution of calcium ions to P2X channel responses.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Mechanism of ivermectin facilitation of human P2X4 receptor channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Single-channel SCAM identifies pore-lining residues in the first extracellular loop and first transmembrane domains of Cx46 hemichannels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Molecular physiology of P2X receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Allosteric control of gating and kinetics at P2X(4) receptor channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Identification of amino acid residues contributing to the pore of a P2X receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Gated access to the pore of a P2X receptor: structural implications for closed-open transitions.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Signaling at purinergic P2X receptors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Cysteine substitution mutagenesis and the effects of methanethiosulfonate reagents at P2X2 and P2X4 receptors support a core common mode of ATP action at P2X receptors.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Cloning and characterization of two novel zebrafish P2X receptor subunits.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Neuronal P2X receptors: localisation and functional properties.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Fractional contribution of calcium to the cation current through glutamate receptor channels

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158179

Preservation and staining of myelinated nerve fibers.

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1017550108

Identification of Amino Acid Residues Contributing to the ATP-binding Site of a Purinergic P2X Receptor

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1017550108

Quantitative measurement of calcium flux through muscle and neuronal nicotinic acetylcholine receptors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21808018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A domain contributing to the ion channel of ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21808018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Substituted-cysteine accessibility method

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21808018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1017550108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808018%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

1 reference

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9 February 2020

PubMed publication ID

21808018

1 reference