Viewpoint: therapeutic implications of CTLA-4 compartmentalization (Q35177419)

6 August 2017

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title

Viewpoint: therapeutic implications of CTLA-4 compartmentalization (English)

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6 August 2017

Miren L Baroja

1

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6 August 2017

Joaquín Madrenas

series ordinal

2

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6 August 2017

language of work or name

English

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publication date

1 August 2003

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American Journal of Transplantation

6 August 2017

published in

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6 August 2017

volume

3

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6 August 2017

issue

8

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6 August 2017

page(s)

919-926

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Structural mechanisms of costimulation

6 August 2017

cites work

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Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength

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7 January 2021

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Immunology. The immunological synapse--a multitasking system

21 January 2018

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Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2

21 January 2018

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7 January 2021

CTLA-4 (CD152) can inhibit T cell activation by two different mechanisms depending on its level of cell surface expression

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The inhibitory function of CTLA-4 does not require its tyrosine phosphorylation

21 January 2018

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21 January 2018

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Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement

21 January 2018

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T lymphocyte costimulation mediated by reorganization of membrane microdomains

21 January 2018

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Polarization of naive CD4+ T cells toward the Th1 subset by CTLA-4 costimulation

21 January 2018

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Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner

21 January 2018

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7 January 2021

Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

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7 January 2021

Signaling through CD28 and CTLA-4 controls two distinct forms of T cell anergy

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7 January 2021

CTLA-4 ligation blocks CD28-dependent T cell activation

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7 January 2021

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

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7 January 2021

CD28 Signaling via VAV/SLP-76 Adaptors

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7 January 2021

CD28 as a molecular amplifier extending TCR ligation and signaling capabilities.

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7 January 2021

B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4.

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7 January 2021

The CD28 signaling pathway regulates glucose metabolism

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7 January 2021

10.1034/J.1600-6143.2003.00182.X

Identifiers

DOI

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6 August 2017

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