The link between the metabolic syndrome and cancer (Q35187561)

7 August 2017

1 reference

8 February 2021

The link between the metabolic syndrome and cancer (English)

1 reference

7 August 2017

1 reference

20 June 2019

1 reference

8 February 2021

3

Derek LeRoith

1 reference

7 August 2017

Sandra Braun

1

1 reference

7 August 2017

Keren Bitton-Worms

series ordinal

2

1 reference

7 August 2017

language of work or name

English

0 references

publication date

16 August 2011

5 references

International Journal of Biological Sciences

7 August 2017

24 March 2019

3 April 2019

20 June 2019

8 February 2021

5 references

7 August 2017

24 March 2019

3 April 2019

20 June 2019

8 February 2021

7

1 reference

7 August 2017

issue

7

1 reference

7 August 2017

page(s)

1003-1015

1 reference

Creative Commons Attribution-NonCommercial-NoDerivatives

7 August 2017

copyright license

4 references

24 March 2019

3 April 2019

20 June 2019

8 February 2021

on focus list of Wikimedia project

ScienceSource

0 references

cites work

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28 July 2018

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Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFkappaB/HIF-1alpha activation

28 July 2018

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28 July 2018

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Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer

28 July 2018

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Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes

28 July 2018

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28 July 2018

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Physical and functional interaction between polyoma virus middle T antigen and insulin and IGF-I receptors is required for oncogene activation and tumour initiation

28 July 2018

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Metabolic syndrome and cancer

28 July 2018

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Metabolic syndrome and risk of cancer mortality in men.

28 July 2018

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Adiponectin inhibits colorectal cancer cell growth through the AMPK/mTOR pathway

28 July 2018

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Emerging role of adipose tissue hypoxia in obesity and insulin resistance

28 July 2018

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HDL-cholesterol and incidence of breast cancer in the ARIC cohort study

28 July 2018

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TNF-alpha increases protein content in C2C12 and primary myotubes by enhancing protein translation via the TNF-R1, PI3K, and MEK.

28 July 2018

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Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

28 July 2018

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Body mass index, physical activity, and risk of multiple myeloma

28 July 2018

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Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.

28 July 2018

1 reference

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Obesity and risk of non-Hodgkin's lymphoma: a meta-analysis

28 July 2018

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IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells

28 July 2018

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Diabetes and risk of endometrial cancer: a population-based prospective cohort study

28 July 2018

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28 July 2018

Cancer statistics, 2007

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Metabolic abnormalities and risk for colorectal cancer in the physicians' health study

28 July 2018

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Peripheral factors in the metabolic syndrome: the pivotal role of adiponectin.

28 July 2018

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Regulation of apoptosis by insulin-like growth factor (IGF)-I.

28 July 2018

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Prevalence of overweight and obesity in the United States, 1999-2004

28 July 2018

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Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes

28 July 2018

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Growth control under stress: mTOR regulation through the REDD1-TSC pathway

28 July 2018

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Studies involving the GH-IGF axis: Lessons from IGF-I and IGF-I receptor gene targeting mouse models.

28 July 2018

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Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications

28 July 2018

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Phosphorylation and binding partner analysis of the TSC1-TSC2 complex

28 July 2018

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The mammalian target of rapamycin signaling network and gene regulation

28 July 2018

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Adipokines: molecular links between obesity and atheroslcerosis

28 July 2018

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Obesity, adipocytokines, and insulin resistance in breast cancer

28 July 2018

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Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

28 July 2018

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Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

C-reactive protein and the risk of incident colorectal cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Insulin and leptin as adiposity signals.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

The insulin-like growth factor system and cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

28 July 2018

1 reference

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The role of the novel adipocyte-derived hormone adiponectin in human disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Adiponectin: a link between excess adiposity and associated comorbidities?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Intra-urban differences in breast cancer mortality: a study from the city of Malmö in Sweden

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Prospective study of adult onset diabetes mellitus (type 2) and risk of colorectal cancer in women

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Expression and function of leptin receptor isoforms in myeloid leukemia and myelodysplastic syndromes: proliferative and anti-apoptotic activities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Role of insulin-like growth factors in embryonic and postnatal growth

28 July 2018

1 reference

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Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Insulin-like growth factor-I receptors are overexpressed and predict a low risk in human breast cancer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Positional cloning of the mouse obese gene and its human homologue

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Molecular and cellular aspects of the insulin-like growth factor I receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Elevated insulin receptor content in human breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Leptin acts as a growth factor for colorectal tumours at stages subsequent to tumour initiation in murine colon carcinogenesis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Can endogenous hyperinsulinaemia explain the increased risk of cancer development and mortality in type 2 diabetes: evidence from mouse models

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

The proliferating role of insulin and insulin-like growth factors in cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Type 2 diabetes and cancer: what is the connection?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Hypercholesterolemia and prostate cancer: a hospital-based case-control study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Effect of weight loss on coronary circulation and adiponectin levels in obese women

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Obesity and colon and rectal cancer risk: a meta-analysis of prospective studies

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Serum high-density lipoprotein cholesterol and risk of non-hodgkin lymphoma.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Effect of obesity on survival in epithelial ovarian cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Introduction: Globalization and the non-communicable disease epidemic

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Leptin improves insulin resistance and hyperglycemia in a mouse model of type 2 diabetes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Metabolic and hormonal profiles: HDL cholesterol as a plausible biomarker of breast cancer risk. The Norwegian EBBA Study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Serum high-density lipoprotein cholesterol, metabolic profile, and breast cancer risk

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

The new kid on the block(ade) of the IGF-1 receptor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Type 2 diabetes and subsequent incidence of breast cancer in the Nurses' Health Study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Mortality from site-specific malignancies in type 2 diabetic patients from Verona

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Leptin: a review of its peripheral actions and interactions

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Body mass index, height, and postmenopausal breast cancer mortality in a prospective cohort of US women

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effects

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

The physiological structure of human C-reactive protein and its complex with phosphocholine

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Circulating tumor necrosis factor-alpha concentrations in a native Canadian population with high rates of type 2 diabetes mellitus.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Somatogenic receptors of rat liver: regulation by insulin.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Elevated C-reactive protein levels in overweight and obese adults

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164150

Enhancement of Insulin-Like Growth Factor Signaling in Human Breast Cancer: Estrogen Regulation of Insulin Receptor Substrate-1 Expressionin Vitroandin Vivo

15 November 2018

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12 December 2020

Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults

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12 December 2020

Insulin-like growth factor I is essential for postnatal growth in response to growth hormone

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12 December 2020

Crosstalk between p53 and nuclear factor-B systems: pro- and anti-apoptotic functions of NF-B

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12 December 2020

The rising incidence of adenocarcinoma relative to squamous cell carcinoma of the uterine cervix in the United States--a 24-year population-based study

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12 December 2020

Targeting the PI3K/AKT/mTOR pathway in non-Hodgkin's lymphoma: results, biology, and development strategies

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12 December 2020

Prostate cancer cell-adipocyte interaction: leptin mediates androgen-independent prostate cancer cell proliferation through c-Jun NH2-terminal kinase

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12 December 2020

Identifiers

DOI

10.7150/IJBS.7.1003

1 reference

7 August 2017

1 reference

7 August 2017

1 reference