Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways (Q39750571)

14 September 2017

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways (English)

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14 September 2017

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Matthias P Wymann

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Giuseppe Lembo

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Giuseppe Lembo

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C. Ronald Kahn

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C Ronald Kahn

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Michael A Crackower

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Seigo Izumo

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Renu Sarao

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Junko Irie-Sasaki

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Tetsuo Shioi

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Gavin Y Oudit

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Ivona Kozieradzki

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14 September 2017

Hui Sun

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Takehiko Sasaki

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14 September 2017

Akira Suzuki

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14 September 2017

Rajan Sah

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14 September 2017

Hai-Ying M Cheng

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Vitalyi O Rybin

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14 September 2017

Luigi Fratta

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Antonio J Oliveira-dos-Santos

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Jeffery L Benovic

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14 September 2017

Susan F Steinberg

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Peter H Backx

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14 September 2017

language of work or name

English

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publication date

1 September 2002

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14 September 2017

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737-749

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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

14 September 2017

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Phospholamban and cardiac contractile function

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Mechanics of left ventricular systolic and diastolic function in physiologic hypertrophy of the athlete's heart

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Angiotensin-converting enzyme 2 is an essential regulator of heart function

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Pten is essential for embryonic development and tumour suppression

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Mechanisms and consequences of activation of protein kinase B/Akt

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Phospholamban and cardiac contractility

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Signaling pathways for cardiac hypertrophy and failure

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Significance of ERK cascade compared with JAK/STAT and PI3-K pathway in gp130-mediated cardiac hypertrophy

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

PI3-kinase/Akt modulates vascular smooth muscle tone via cAMP signaling pathways

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Beta 2-adrenergic receptor actions in neonatal and adult rat ventricular myocytes

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Protein-protein interactions at G-protein-coupled receptors

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by beta-adrenergic receptor kinase 1. A role in receptor sequestration

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Beta-adrenergic axis and heart disease

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Angiotensin II induces activation of phosphatidylinositol 3-kinase in cardiomyocytes

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Seven-transmembrane-spanning receptors and heart function

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Inhibition of calcineurin and sarcolemmal Ca2+ influx protects cardiac morphology and ventricular function in K(v)4.2N transgenic mice

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Akt/protein kinase B promotes organ growth in transgenic mice

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Thrombin modulates phosphoinositide metabolism, cytosolic calcium, and impulse initiation in the heart

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Characteristics of the beta-adrenergic receptor complex in the epicardial border zone of the 5-day infarcted canine heart

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Receptor stimulated accumulation of phosphatidylinositol (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Signalling through the lipid products of phosphoinositide-3-OH kinase

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

The transgenic expression of highly inhibitory monomeric forms of phospholamban in mouse heart impairs cardiac contractility

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900969-8

7 January 2021

10.1016/S0092-8674(02)00969-8

Identifiers

DOI

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14 September 2017

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