Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanisms (Q35204583)

7 August 2017

title

Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanisms (English)

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7 August 2017

John Monahan

12

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Nathanael Gray

11

object named as

Nathanael S Gray

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7 August 2017

14

Rameen Beroukhim

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7 August 2017

15

Gordon B Mills

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7 August 2017

Pixu Liu

1

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7 August 2017

Hailing Cheng

2

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7 August 2017

Stephanie Santiago

3

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7 August 2017

Maria Raeder

4

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7 August 2017

Fan Zhang

5

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7 August 2017

Adam Isabella

6

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7 August 2017

Janet Yang

7

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7 August 2017

Derek J Semaan

8

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7 August 2017

Changzhong Chen

9

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7 August 2017

Edward A Fox

10

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7 August 2017

Robert Schlegel

13

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7 August 2017

Jean J Zhao

16

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7 August 2017

language of work or name

English

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publication date

7 August 2011

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7 August 2017

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7 August 2017

volume

17

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7 August 2017

issue

9

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7 August 2017

page(s)

1116-1120

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Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway

7 August 2017

cites work

1 reference

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13 July 2018

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13 July 2018

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Targeting the phosphoinositide 3-kinase pathway in cancer

13 July 2018

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Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941

13 July 2018

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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

13 July 2018

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PI3K pathway alterations in cancer: variations on a theme

13 July 2018

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An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

13 July 2018

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Cancer-specific mutations in phosphatidylinositol 3-kinase

13 July 2018

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An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms

13 July 2018

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MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

13 July 2018

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Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.

13 July 2018

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Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

13 July 2018

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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

13 July 2018

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The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells

13 July 2018

1 reference

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Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells

13 July 2018

1 reference

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The transcriptional repressor Snail promotes mammary tumor recurrence

13 July 2018

1 reference

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Mutant PIK3CA promotes cell growth and invasion of human cancer cells

13 July 2018

1 reference

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Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

13 July 2018

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An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays

13 July 2018

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A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

13 July 2018

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High frequency of mutations of the PIK3CA gene in human cancers

13 July 2018

1 reference

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A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology

13 July 2018

1 reference

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

13 July 2018

1 reference

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Determination of subcutaneous tumor size in athymic (nude) mice

13 July 2018

1 reference

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Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis

13 July 2018

1 reference

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High-resolution genomic and expression analyses of copy number alterations in breast tumors

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21822287

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.2402

1 reference

7 August 2017

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7 August 2017

1 reference