Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine (Q35209685)

7 August 2017

title

Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine (English)

1 reference

7 August 2017

1

Rupesh Dash

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7 August 2017

11

David T Curiel

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7 August 2017

9

Paul Dent

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7 August 2017

Joanna E Richards

2

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7 August 2017

Zhao-Zhong Su

3

1 reference

7 August 2017

Sujit K Bhutia

4

1 reference

7 August 2017

Belal Azab

5

1 reference

7 August 2017

Mohamed Rahmani

6

1 reference

7 August 2017

Girija Dasmahapatra

7

1 reference

7 August 2017

Adly Yacoub

8

1 reference

7 August 2017

Igor P Dmitriev

10

1 reference

7 August 2017

Steven Grant

12

1 reference

7 August 2017

Maurizio Pellecchia

13

1 reference

7 August 2017

John C Reed

14

1 reference

7 August 2017

Devanand Sarkar

15

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7 August 2017

Paul B Fisher

16

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7 August 2017

language of work or name

English

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publication date

25 May 2010

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7 August 2017

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7 August 2017

volume

70

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7 August 2017

issue

12

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7 August 2017

page(s)

5034-5045

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Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells

7 August 2017

cites work

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Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24.

13 July 2018

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Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis

13 July 2018

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Secretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24

13 July 2018

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Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells

13 July 2018

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mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).

13 July 2018

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Translational repression of MCL-1 couples stress-induced eIF2 alpha phosphorylation to mitochondrial apoptosis initiation

13 July 2018

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The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress

13 July 2018

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Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?

13 July 2018

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Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation

13 July 2018

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N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity

13 July 2018

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BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis

13 July 2018

1 reference

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Melanoma differentiation-associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model

13 July 2018

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mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

13 July 2018

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Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease

13 July 2018

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Is mda-7/IL-24 a "magic bullet" for cancer?

13 July 2018

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Endoplasmic reticulum stress: cell life and death decisions.

13 July 2018

1 reference

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Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation

13 July 2018

1 reference

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Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells

13 July 2018

1 reference

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Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

13 July 2018

1 reference

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Eukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chloride

13 July 2018

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13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Interleukin-10 and related cytokines and receptors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

13 July 2018

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Gene therapy of prostate cancer: current and future directions

13 July 2018

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mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

13 July 2018

1 reference

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Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171699

Methods for isolation and analysis of polyribosomes

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20501829

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20501829

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20501829

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-10-0563

1 reference

7 August 2017

1 reference

7 August 2017

1 reference