Emergence of the metabolic syndrome in childhood: an epidemiological overview and mechanistic link to dyslipidemia (Q35209848)

7 August 2017

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title

Emergence of the metabolic syndrome in childhood: an epidemiological overview and mechanistic link to dyslipidemia (English)

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7 August 2017

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Rita Kohen-Avramoglu

1

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PubMed ID

12951167

7 August 2017

Andre Theriault

series ordinal

2

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PubMed ID

12951167

7 August 2017

Khosrow Adeli

series ordinal

3

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7 August 2017

1 September 2003

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7 August 2017

Clinical Biochemistry

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7 August 2017

36

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7 August 2017

413-420

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7 August 2017

6

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Persistent elevation of plasma insulin levels is associated with increased cardiovascular risk in children and young adults. The Bogalusa Heart Study

7 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Relationship of childhood obesity to coronary heart disease risk factors in adulthood: the Bogalusa Heart Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Global and societal implications of the diabetes epidemic

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Prevalence of glucose intolerance among Native Hawaiians in two rural communities. Native Hawaiian Health Research (NHHR) Project

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Prevalence of diabetes and its risk factors in China, 1994. National Diabetes Prevention and Control Cooperative Group.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Rising prevalence of NIDDM in an urban population in India

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

The thrifty genotype in non-insulin dependent diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Development of obesity and insulin resistance in the Israeli sand rat (Psammomys obesus). Does leptin play a role?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Beacon: a novel gene involved in the regulation of energy balance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Increased incidence of non-insulin-dependent diabetes mellitus among adolescents.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Prevalence of impaired glucose tolerance among children and adolescents with marked obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Increased incidence of non-insulin dependent diabetes mellitus among Japanese schoolchildren correlates with an increased intake of animal protein and fat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Summary measures of the insulin resistance syndrome are adverse among Mexican-American versus non-Hispanic white children: the Corpus Christi Child Heart Study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Early evidence of ethnic differences in cardiovascular risk: cross sectional comparison of British South Asian and white children

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Evaluation of the insulin resistance syndrome in 5- to 10-year-old overweight/obese African-American children

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Syndrome X in 8-y-old Australian children: stronger associations with current body fatness than with infant size or growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Insulin resistance syndrome in childhood: associations of the euglycemic insulin clamp and fasting insulin with fatness and other risk factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Adiposity in childhood predicts obesity and insulin resistance in young adulthood

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Childhood obesity: the health issue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

The association of cardiovascular risk factor clustering related to insulin resistance syndrome (Syndrome X) between young parents and their offspring: the Bogalusa Heart Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Putting the genes for type II diabetes on the map

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Recent advances in the genetics of severe childhood obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Obesity associated with a mutation in a genetic regulator of adipocyte differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

The Search for Human Obesity Genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Aetiology of overweight and obesity in children and adolescents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Insulin resistance and the metabolic syndrome-a challenge of the new millennium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Relation of serum lipoprotein levels and systolic blood pressure to early atherosclerosis. The Bogalusa Heart Study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Tracking of serum lipids and lipoproteins from childhood to dyslipidemia in adults: the Bogalusa Heart Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Low-density lipoprotein subclasses in children under 10 years of age.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Presence of increased stiffness of the common carotid artery and endothelial dysfunction in severely obese children: a prospective study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Interaction between free fatty acids and insulin in the acute control of very low density lipoprotein production in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Disordered Fat Storage and Mobilization in the Pathogenesis of Insulin Resistance and Type 2 Diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Studies on the mechanism of insulin resistance in the liver from humans with noninsulin-dependent diabetes. Insulin action and binding in isolated hepatocytes, insulin receptor structure, and kinase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Insulin action in skeletal muscle from patients with NIDDM.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Decreased insulin binding to adipocytes and circulating monocytes from obese subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Pioglitazone improves insulin signaling defects in skeletal muscle from Wistar fatty (fa/fa) rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Disruption of IRS-2 causes type 2 diabetes in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Coordinated action of protein tyrosine phosphatases in insulin signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Insulin receptor and epidermal growth factor receptor dephosphorylation by three major rat liver protein-tyrosine phosphatases expressed in a recombinant bacterial system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Protein-tyrosine phosphatases PTP1B and syp are modulators of insulin-stimulated translocation of GLUT4 in transfected rat adipose cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Thiazolidine derivatives ameliorate high glucose-induced insulin resistance via the normalization of protein-tyrosine phosphatase activities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Nutritionally induced insulin resistance and receptor defect leading to beta-cell failure in animal models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

A new rat model of type 2 diabetes: the fat-fed, streptozotocin-treated rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Serum lipids and lipoproteins in the atherosclerosis prone LA/N corpulent rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Post-transcriptional stimulation of the assembly and secretion of triglyceride-rich apolipoprotein B lipoproteins in a mouse with selective deficiency of brown adipose tissue, obesity, and insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus: overexpression of protein kinase Cepsilon in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Circulating lipoproteins and hepatic sterol metabolism in Psammomys obesus prone to obesity, hyperglycemia and hyperinsulinemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed ham

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-contain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-9120%2803%2900038-9

10.1016/S0009-9120(03)00038-9

7 January 2021

Identifiers

DOI

1 reference

7 August 2017

1 reference

PubMed ID

12951167