c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3. (Q35222270)

7 August 2017

title

c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3. (English)

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7 August 2017

12

Jane E Visvader

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7 August 2017

11

Geoffrey J Lindeman

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7 August 2017

2

François Vaillant

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7 August 2017

Kate D Sutherland

1

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7 August 2017

Warren S Alexander

3

1 reference

7 August 2017

Tim M Wintermantel

4

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7 August 2017

Natasha C Forrest

5

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7 August 2017

Sheridan L Holroyd

6

1 reference

7 August 2017

Edward J McManus

7

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7 August 2017

Gunther Schutz

8

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7 August 2017

Christine J Watson

9

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7 August 2017

Lewis A Chodosh

10

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7 August 2017

language of work or name

English

0 references

publication date

30 November 2006

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7 August 2017

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7 August 2017

volume

25

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7 August 2017

issue

24

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7 August 2017

page(s)

5805-5815

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Socs2 and elf5 mediate prolactin-induced mammary gland development

7 August 2017

cites work

1 reference

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Oncostatin M receptor-mediated signal transduction is negatively regulated by SOCS3 through a receptor tyrosine-independent mechanism.

27 July 2018

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Generation of a functional mammary gland from a single stem cell

27 July 2018

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The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development.

27 July 2018

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Genetic reduction of embryonic leukemia-inhibitory factor production rescues placentation in SOCS3-null embryos but does not prevent inflammatory disease

27 July 2018

1 reference

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Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development.

27 July 2018

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Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition

27 July 2018

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Developmental stage determines the effects of MYC in the mammary epithelium

27 July 2018

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Regulation of matrix biology by matrix metalloproteinases

27 July 2018

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Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

27 July 2018

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Bim is a suppressor of Myc-induced mouse B cell leukemia

27 July 2018

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The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

27 July 2018

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The Bcl-2 family: roles in cell survival and oncogenesis.

27 July 2018

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Metalloproteinases and their inhibitors in angiogenesis.

27 July 2018

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Selective involvement of TIMP-2 in the second activational cleavage of pro-MMP-2: refinement of the pro-MMP-2 activation mechanism

27 July 2018

1 reference

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SOCS3 negatively regulates IL-6 signaling in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation

27 July 2018

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Targeted deletion of the Tsg101 gene results in cell cycle arrest at G1/S and p53-independent cell death

27 July 2018

1 reference

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Targeting mammary epithelial cells using a bacterial artificial chromosome

27 July 2018

1 reference

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E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination

27 July 2018

1 reference

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Accelerated apoptosis in the Timp-3-deficient mammary gland

27 July 2018

1 reference

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27 July 2018

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Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Bax is a transcriptional target and mediator of c-myc-induced apoptosis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

SOCS3 is essential in the regulation of fetal liver erythropoiesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Cytokine-inducible SH2 protein (CIS3) and JAK2 binding protein (JAB) abolish prolactin receptor-mediated STAT5 signaling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

STAT3 is required for the gp130-mediated full activation of the c-myc gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Cre-mediated gene deletion in the mammary gland

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Differential activation of STATs 3 and 5 during mammary gland development.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Information networks in the mammary gland.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Hepatocyte proliferation and tissue remodeling is impaired after liver injury in oncostatin M receptor knockout mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Suppressors of cytokine signaling and immunity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

SOCS3 regulates the plasticity of gp130 signaling

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Regulation and function of the cytokine-inducible SH-2 domain proteins, CIS and SOCS3, in mammary epithelial cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Gain of Bcl-2 is more potent than bax loss in regulating mammary epithelial cell survival in vivo

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Generalized lacZ expression with the ROSA26 Cre reporter strain

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Efficient BLG-Cre mediated gene deletion in the mammary gland.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698901

Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture

26 September 2018

1 reference

12 December 2020

Tissue-specific induction of SOCS gene expression by PRL

1 reference

12 December 2020

Loss of interleukin 6 results in delayed mammary gland involution: a possible role for mitogen-activated protein kinase and not signal transducer and activator of transcription 3

1 reference

12 December 2020

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1 reference

12 December 2020

Ha-ras and c-myc oncogene expression interferes with morphological and functional differentiation of mammary epithelial cells in single and double transgenic mice

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7601455

1 reference

7 August 2017

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7 August 2017

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