The evolution of drug resistance in clinical isolates of Candida albicans (Q35248451)

7 August 2017

title

The evolution of drug resistance in clinical isolates of Candida albicans (English)

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7 August 2017

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10

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12

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5

Candace Guiducci

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Aviv Regev

14

object named as

Aviv Regev

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7 August 2017

Toni Delorey

7

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Theodore C White

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Theodore C White

9

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Darren Abbey

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object named as

Darren Abbey

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7 August 2017

Christopher B Ford

1

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7 August 2017

Jason M Funt

2

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Luca Issi

4

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7 August 2017

Diego A Martinez

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7 August 2017

Bi Yu Li

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7 August 2017

Reeta P Rao

11

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7 August 2017

Dawn A Thompson

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7 August 2017

language of work or name

English

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publication date

3 February 2015

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7 August 2017

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7 August 2017

volume

4

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7 August 2017

page(s)

e00662

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The APSES transcription factor Efg1 is a global regulator that controls morphogenesis and biofilm formation in Candida parapsilosis.

7 August 2017

cites work

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27 July 2018

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Gene copy-number alterations: a cost-benefit analysis

27 July 2018

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The 'obligate diploid' Candida albicans forms mating-competent haploids

27 July 2018

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Dynamic large-scale chromosomal rearrangements fuel rapid adaptation in yeast populations

27 July 2018

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The role of Candida albicans AP-1 protein against host derived ROS in in vivo models of infection.

27 July 2018

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Improved gene ontology annotation for biofilm formation, filamentous growth, and phenotypic switching in Candida albicans

27 July 2018

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Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata

27 July 2018

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Importance of the Candida albicans cell wall during commensalism and infection.

27 July 2018

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27 July 2018

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A recently evolved transcriptional network controls biofilm development in Candida albicans

27 July 2018

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Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

27 July 2018

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Stress-induced loss of heterozygosity in Candida: a possible missing link in the ability to evolve

27 July 2018

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Stress alters rates and types of loss of heterozygosity in Candida albicans

27 July 2018

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Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1.

27 July 2018

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Immunosensing during colonization by Candida albicans: does it take a village to colonize the intestine?

27 July 2018

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Integrative genomics viewer

27 July 2018

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Loss of heterozygosity at an unlinked genomic locus is responsible for the phenotype of a Candida albicans sap4Δ sap5Δ sap6Δ mutant

27 July 2018

1 reference

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Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast

27 July 2018

1 reference

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Identification of aneuploidy-tolerating mutations

27 July 2018

1 reference

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Variable tandem repeats accelerate evolution of coding and regulatory sequences.

27 July 2018

1 reference

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Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity

27 July 2018

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Genomic Plasticity of the Human Fungal Pathogen Candida albicans

27 July 2018

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Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance

27 July 2018

1 reference

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Gene Ontology and the annotation of pathogen genomes: the case of Candida albicans

27 July 2018

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Evolution of pathogenicity and sexual reproduction in eight Candida genomes

27 July 2018

1 reference

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Stress-induced phenotypic switching in Candida albicans

27 July 2018

1 reference

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Fast and accurate short read alignment with Burrows-Wheeler transform

27 July 2018

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Evolution in Candida albicans populations during a single passage through a mouse host

27 July 2018

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The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast

27 July 2018

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Mutations in the multi-drug resistance regulator MRR1, followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains

27 July 2018

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The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains

27 July 2018

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The Yak1 kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans

27 July 2018

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The impact of next-generation sequencing technology on genetics

27 July 2018

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Mutation as a stress response and the regulation of evolvability

27 July 2018

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Discovering the secrets of the Candida albicans agglutinin-like sequence (ALS) gene family--a sticky pursuit

27 July 2018

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The competitive cost of antibiotic resistance in Mycobacterium tuberculosis

27 July 2018

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27 July 2018

1 reference

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A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383195

Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383195

Alternative Candida albicans lifestyles: growth on surfaces

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383195

Intragenic tandem repeats generate functional variability

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383195

Regulation of cell-surface genes and biofilm formation by the C. albicans transcription factor Bcr1p

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383195

Mating in Candida albicans and the search for a sexual cycle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383195

Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383195

Demonstration of loss of heterozygosity by single-nucleotide polymorphism microarray analysis and alterations in strain morphology in Candida albicans strains during infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383195

Genome-wide single-nucleotide polymorphism map for Candida albicans

27 July 2018

1 reference

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Functional and structural diversity in the Als protein family of Candida albicans

27 July 2018

1 reference

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Metagenes and molecular pattern discovery using matrix factorization

27 July 2018

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Driving change: the evolution of alternative genetic codes.

27 July 2018

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Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C.albicans

27 July 2018

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Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae

27 July 2018

1 reference

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Evolution of drug resistance in Candida albicans

27 July 2018

1 reference

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Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae

27 July 2018

1 reference

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Resistance mechanisms in clinical isolates of Candida albicans

27 July 2018

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Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients

27 July 2018

1 reference

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Biofilm formation by the fungal pathogen Candida albicans: development, architecture, and drug resistance

27 July 2018

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Bakers' yeast, a model for fungal biofilm formation.

27 July 2018

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A G1 cyclin is necessary for maintenance of filamentous growth in Candida albicans

27 July 2018

1 reference

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Formation of azole-resistant Candida albicans by mutation of sterol 14-demethylase P450

27 July 2018

1 reference

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Candida albicans ALS3 and insights into the nature of the ALS gene family

27 July 2018

1 reference

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Hospital specificity, region specificity, and fluconazole resistance of Candida albicans bloodstream isolates

27 July 2018

1 reference

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Nonfilamentous C. albicans mutants are avirulent

27 July 2018

1 reference

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The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14alpha demethylase in Candida albicans

27 July 2018

1 reference

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Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383195

Candida colonization and subsequent infections in critically ill surgical patients

27 July 2018

1 reference

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Chromosomal duplication is a transient evolutionary solution to stress.

27 July 2018

1 reference

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The Candida genome database incorporates multiple Candida species: multispecies search and analysis tools with curated gene and protein information for Candida albicans and Candida glabrata

26 September 2018

1 reference

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Full-length transcriptome assembly from RNA-Seq data without a reference genome

26 September 2018

1 reference

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Candida albicans, a major human fungal pathogen

26 September 2018

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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

26 September 2018

1 reference

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A pathogenesis assay using Saccharomyces cerevisiae and Caenorhabditis elegans reveals novel roles for yeast AP-1, Yap1, and host dual oxidase BLI-3 in fungal pathogenesis

26 September 2018

1 reference

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An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1.

26 September 2018

1 reference

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cis-Acting elements within the Candida albicans ERG11 promoter mediate the azole response through transcription factor Upc2p

26 September 2018

1 reference

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In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination

26 September 2018

1 reference

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Aneuploidy and isochromosome formation in drug-resistant Candida albicans

26 September 2018

1 reference

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A switch from high-fidelity to error-prone DNA double-strand break repair underlies stress-induced mutation.

26 September 2018

1 reference

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Attributable mortality of nosocomial candidemia, revisited

26 September 2018

1 reference

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Candidemia in critically ill patients: difference of outcome between medical and surgical patients

26 September 2018

1 reference

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A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients.

26 September 2018

1 reference

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Genome-wide identification of fungal GPI proteins.

26 September 2018

1 reference

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A randomized and blinded multicenter trial of high-dose fluconazole plus placebo versus fluconazole plus amphotericin B as therapy for candidemia and its consequences in nonneutropenic subjects.

26 September 2018

1 reference

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Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans

26 September 2018

1 reference

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Nosocomial bloodstream infections in pediatric patients in United States hospitals: epidemiology, clinical features and susceptibilities

26 September 2018

1 reference

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MALDI-TOF mass spectrometry-based SNP genotyping

26 September 2018

1 reference

12 December 2020

The cost of antibiotic resistance from a bacterial perspective

1 reference

12 December 2020

The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans

1 reference

12 December 2020

Ploidy controls the success of mutators and nature of mutations during budding yeast evolution

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12 December 2020

A randomized trial comparing fluconazole with amphotericin B for the treatment of candidemia in patients without neutropenia. Candidemia Study Group and the National Institute

1 reference

12 December 2020

Identifiers

DOI

10.7554/ELIFE.00662

1 reference

7 August 2017

1 reference

7 August 2017

1 reference