Eg5 steps it up! (Q35253269)

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Language	Label	Description	Also known as
English	Eg5 steps it up!	scientific article

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scholarly article

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

Eg5 steps it up! (English)

1 reference

Europe PubMed Central

7 August 2017

Steven M. Block

3

0 references

author name string

Megan T Valentine

1

1 reference

Europe PubMed Central

7 August 2017

Polly M Fordyce

2

1 reference

Europe PubMed Central

7 August 2017

publication date

15 December 2006

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

1

1 reference

Europe PubMed Central

7 August 2017

31

1 reference

Europe PubMed Central

7 August 2017

https://scigraph.springernature.com/pub.10.1186/1747-1028-1-31

0 references

Allosteric inhibition of kinesin-5 modulates its processive directional motility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Backsteps induced by nucleotide analogs suggest the front head of kinesin is gated by strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

A structural model for monastrol inhibition of dimeric kinesin Eg5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Kinesin 5-independent poleward flux of kinetochore microtubules in PtK1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Functional roles of poleward microtubule flux during mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

A mitotic lamin B matrix induced by RanGTP required for spindle assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Efficient mitosis in human cells lacking poleward microtubule flux

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Mechanism and function of poleward flux in Xenopus extract meiotic spindles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

A mechanistic model for the organization of microtubule asters by motor and non-motor proteins in a mammalian mitotic extract.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Kinesin walks hand-over-hand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Stepping and stretching. How kinesin uses internal strain to walk processively

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Probing the kinesin reaction cycle with a 2D optical force clamp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

A force balance model of early spindle pole separation in Drosophila embryos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Poleward microtubule flux is a major component of spindle dynamics and anaphase a in mitotic Drosophila embryos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Searching for a spindle matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Mitosis, microtubules, and the matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Switch-based mechanism of kinesin motors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

The spindle: a dynamic assembly of microtubules and motors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Mechanism of the single-headed processivity: diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Opposing motor activities are required for the organization of the mammalian mitotic spindle pole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Crystal structure of the kinesin motor domain reveals a structural similarity to myosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

The kinesin-like protein KLP61F is essential for mitosis in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

A "slow" homotetrameric kinesin-related motor protein purified from Drosophila embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Bead movement by single kinesin molecules studied with optical tweezers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Myosin step size. Estimation from slow sliding movement of actin over low densities of heavy meromyosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Poleward microtubule flux mitotic spindles assembled in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Cloning by differential screening of a Xenopus cDNA that encodes a kinesin-related protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

Mitotic spindle organization by a plus-end-directed microtubule motor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

27 July 2018

The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Docking and rolling, a model of how the mitotic motor Eg5 works

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Mechanics of the kinesin step.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Spindle microtubules in flux.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Poly(ADP-ribose) is required for spindle assembly and structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

KIF1A alternately uses two loops to bind microtubules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Monastrol stabilises an attached low-friction mode of Eg5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Kinesin moves by an asymmetric hand-over-hand mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Kinesin's processivity results from mechanical and chemical coordination between the ATP hydrolysis cycles of the two motor domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

A processive single-headed motor: kinesin superfamily protein KIF1A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Crystal structure of the motor domain of the kinesin-related motor ncd.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Working strokes by single molecules of the kinesin-related microtubule motor ncd

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716758

26 September 2018

Alternate fast and slow stepping of a heterodimeric kinesin molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/17173688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanometres and piconewtons: the macromolecular mechanics of kinesin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17173688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinesin-related cut7 protein associates with mitotic and meiotic spindles in fission yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/17173688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monomeric kinesin head domains hydrolyze multiple ATP molecules before release from a microtubule

1 reference

https://pubmed.ncbi.nlm.nih.gov/17173688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic evidence for low chemical processivity in ncd and Eg5

1 reference

https://pubmed.ncbi.nlm.nih.gov/17173688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NuMA is a component of an insoluble matrix at mitotic spindle poles

1 reference

https://pubmed.ncbi.nlm.nih.gov/17173688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motility of dimeric ncd on a metal-chelating surfactant: evidence that ncd is not processive

1 reference

https://pubmed.ncbi.nlm.nih.gov/17173688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1747-1028-1-31

1 reference

Europe PubMed Central

7 August 2017

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1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

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