A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis. (Q35339915)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662829%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis (English)

1 reference

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12 March 2020

1 reference

16

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12 March 2020

Sudha Sharma

17

1 reference

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12 March 2020

Lalage M Wakefield

18

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12 March 2020

author name string

M Subramanian

1

1 reference

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12 March 2020

P Francis

2

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12 March 2020

S Bilke

3

1 reference

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12 March 2020

X L Li

4

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12 March 2020

T Hara

5

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12 March 2020

X Lu

6

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12 March 2020

M F Jones

7

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12 March 2020

R L Walker

8

1 reference

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12 March 2020

Y Zhu

9

1 reference

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12 March 2020

M Pineda

10

1 reference

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12 March 2020

C Lee

11

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12 March 2020

L Varanasi

12

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12 March 2020

Y Yang

13

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12 March 2020

L A Martinez

14

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12 March 2020

J Luo

15

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12 March 2020

P S Meltzer

19

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12 March 2020

A Lal

20

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12 March 2020

language of work or name

English

0 references

publication date

24 March 2014

1 reference

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12 March 2020

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12 March 2020

volume

34

1 reference

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12 March 2020

issue

9

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12 March 2020

page(s)

1094-1104

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Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression

12 March 2020

cites work

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On measuring miRNAs after transient transfection of mimics or antisense inhibitors

12 July 2018

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12 July 2018

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MicroRNAs in the p53 network: micromanagement of tumour suppression

12 July 2018

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Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis.

12 July 2018

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Mutant p53 drives invasion in breast tumors through up-regulation of miR-155.

12 July 2018

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Mutant p53: one name, many proteins

12 July 2018

1 reference

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Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion

12 July 2018

1 reference

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Mutant p53 cooperates with ETS2 to promote etoposide resistance

12 July 2018

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miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay

12 July 2018

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High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer

12 July 2018

1 reference

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RAC1 activation mediates Twist1-induced cancer cell migration

12 July 2018

1 reference

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An alternative mode of microRNA target recognition

12 July 2018

1 reference

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Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

12 July 2018

1 reference

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MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function

12 July 2018

1 reference

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Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling

12 July 2018

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The Lin28/let-7 axis regulates glucose metabolism

12 July 2018

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TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.

12 July 2018

1 reference

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A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

12 July 2018

1 reference

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Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML.

12 July 2018

1 reference

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LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms

12 July 2018

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12 July 2018

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Desperately seeking microRNA targets

12 July 2018

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Modulation of the vitamin D3 response by cancer-associated mutant p53

12 July 2018

1 reference

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Mutant p53 drives invasion by promoting integrin recycling

12 July 2018

1 reference

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NFkappaB p50-CCAAT/enhancer-binding protein beta (C/EBPbeta)-mediated transcriptional repression of microRNA let-7i following microbial infection

12 July 2018

1 reference

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miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

12 July 2018

1 reference

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Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

12 July 2018

1 reference

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MicroRNAs: target recognition and regulatory functions

12 July 2018

1 reference

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A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

12 July 2018

1 reference

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The let-7 family of microRNAs

12 July 2018

1 reference

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The impact of microRNAs on protein output

12 July 2018

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The let-7 microRNA reduces tumor growth in mouse models of lung cancer

12 July 2018

1 reference

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The let-7 microRNA represses cell proliferation pathways in human cells

12 July 2018

1 reference

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A microRNA component of the p53 tumour suppressor network

12 July 2018

1 reference

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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

12 July 2018

1 reference

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Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

12 July 2018

1 reference

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Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

A global map of p53 transcription-factor binding sites in the human genome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

Tumor-derived p53 mutants induce NF-kappaB2 gene expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

RAS is regulated by the let-7 microRNA family

12 July 2018

1 reference

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Live or let die: the cell's response to p53

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

12 July 2018

1 reference

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

Activation of c-myc Gene Expression by Tumor-Derived p53 Mutants Requires a Discrete C-Terminal Domain

12 July 2018

1 reference

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Mutations in the p53 gene occur in diverse human tumour types

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391367

Chemosensitivity linked to p73 function

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2014.46

Inflammation and IGF-I activate the Akt pathway in breast cancer

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2014.46

31 March 2020

Identifiers

DOI

10.1038/ONC.2014.46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662829%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662829%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

24662829

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662829%20AND%20SRC:MED&resulttype=core&format=json