Enhancement of TGF-β signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer (Q35360788)

7 August 2017

Enhancement of TGF-β signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer (English)

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7 August 2017

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Vikas Sharma

1

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7 August 2017

Anna G Antonacopoulou

2

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7 August 2017

Shinya Tanaka

3

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7 August 2017

Alexios A Panoutsopoulos

4

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7 August 2017

Vasiliki Bravou

5

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7 August 2017

Haralabos P Kalofonos

6

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7 August 2017

Vasso Episkopou

7

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7 August 2017

language of work or name

English

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publication date

1 October 2011

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7 August 2017

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7 August 2017

71

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7 August 2017

20

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7 August 2017

6438-6449

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describes a project that uses

7 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3194767/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells.

12 July 2018

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12 July 2018

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12 July 2018

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Ski and SnoN, potent negative regulators of TGF-beta signaling

12 July 2018

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12 July 2018

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Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation

12 July 2018

1 reference

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Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling

12 July 2018

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The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer

12 July 2018

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Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover

12 July 2018

1 reference

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12 July 2018

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12 July 2018

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Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia

12 July 2018

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Alterations in components of the TGF-beta superfamily signaling pathways in human cancer

12 July 2018

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Specificity and versatility in tgf-beta signaling through Smads

12 July 2018

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Signaling pathways in intestinal development and cancer

12 July 2018

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BRCA1 mRNA expression levels as an indicator of chemoresistance in lung cancer

12 July 2018

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Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

12 July 2018

1 reference

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A novel inflammation‐related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate

12 July 2018

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Serrated adenomas and mixed polyposis caused by a splice acceptor deletion in the mouse Smad4 gene

12 July 2018

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Arkadia enhances nodal-related signalling to induce mesendoderm

12 July 2018

1 reference

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Induction of the mammalian node requires Arkadia function in the extraembryonic lineages

12 July 2018

1 reference

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Gastrointestinal tumorigenesis in Smad4 (Dpc4) mutant mice

12 July 2018

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Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

12 July 2018

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12 July 2018

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12 July 2018

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AOM-induced mouse colon tumors do not express full-length APC protein

12 July 2018

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12 July 2018

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TGF-beta repressors SnoN and Ski are implicated in human colorectal carcinogenesis.

12 July 2018

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Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation.

26 September 2018

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ILK over-expression in human colon cancer progression correlates with activation of beta-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway

26 September 2018

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Loss of heterozygosity and nonsense mutation in Apc in azoxymethane-induced colonic tumours in min mice.

26 September 2018

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26 September 2018

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Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane

26 September 2018

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12 December 2020

SMAD7 is a prognostic marker in patients with colorectal cancer

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12 December 2020

Smad4 haploinsufficiency in mouse models for intestinal cancer

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12 December 2020

Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing

1 reference

12 December 2020

10.1158/0008-5472.CAN-11-1645

Identifiers

DOI

1 reference

release_nu6j7klvvfhshlwhopnc4zxssu

7 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/nu6j7klvvfhshlwhopnc4zxssu

24 November 2022

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PMCID

3194767

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7 August 2017

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