Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling (Q24306193)

ubiquitin protein ligase binding

GOA release 2020-03-11

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GOA release 2020-03-11

Ring finger 111

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GOA release 2020-03-11

author name string

Yoshiko Nagano

1

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Konstantinos J Mavrakis

2

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Kian Leong Lee

3

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Tomoko Fujii

4

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Daizo Koinuma

5

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Hitoshi Sase

6

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Keiko Yuki

7

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Kazunobu Isogaya

8

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Masao Saitoh

9

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Takeshi Imamura

10

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Vasso Episkopou

11

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Kohei Miyazono

12

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Keiji Miyazawa

Journal of Biological Chemistry

13

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language of work or name

English

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publication date

13 July 2007

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published in

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volume

282

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issue

28

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page(s)

20492-501

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cites work

Smads as transcriptional co-modulators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

New insights into TGF-beta-Smad signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Two major Smad pathways in TGF-beta superfamily signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

TGFbeta signaling in growth control, cancer, and heritable disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Role of transforming growth factor beta in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Deficient Smad7 expression: a putative molecular defect in scleroderma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

SNO is a probable target for gene amplification at 3q26 in squamous-cell carcinomas of the esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Increased expression of c-Ski as a co-repressor in transforming growth factor-beta signaling correlates with progression of esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Amplification of SKI is a prognostic marker in early colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Induction of the mammalian node requires Arkadia function in the extraembryonic lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Arkadia enhances nodal-related signalling to induce mesendoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Nuclear and cytoplasmic c-Ski differently modulate cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Ski and SnoN: negative regulators of TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Isolation of human cDNA clones of ski and the ski-related gene, sno

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Proto-oncogene Sno expression, alternative isoforms and immediate early serum response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

DAF-5 is a Ski oncoprotein homolog that functions in a neuronal TGF beta pathway to regulate C. elegans dauer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

c-Ski activates MyoD in the nucleus of myoblastic cells through suppression of histone deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Dual role of SnoN in mammalian tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Smad7 promotes and enhances skeletal muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Sumoylated SnoN represses transcription in a promoter-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

The Ski protein family is required for MeCP2-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

Repression of endogenous Smad7 by Ski.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

SnoN co-repressor binds and represses smad7 gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

E1A inhibits transforming growth factor-beta signaling through binding to Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701294200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M701294200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

17510063

1 reference

Consolidated OpenCitations Corpus – April 2017