Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis. (Q35374941)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25818302%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis (English)

1 reference

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3 March 2020

8

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3 March 2020

author name string

Hua Tian

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25818302%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Brian Biehs

2

1 reference

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3 March 2020

Cecilia Chiu

3

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3 March 2020

Christian W Siebel

4

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3 March 2020

Yan Wu

5

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3 March 2020

Mike Costa

6

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3 March 2020

Frederic J de Sauvage

7

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3 March 2020

publication date

26 March 2015

1 reference

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3 March 2020

1 reference

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3 March 2020

volume

11

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3 March 2020

issue

1

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3 March 2020

page(s)

33-42

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R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5

3 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Lrp5 and Lrp6 play compensatory roles in mouse intestinal development

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Therapeutic antibody targeting of individual Notch receptors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Beta-catenin up-regulates Atoh1 expression in neural progenitor cells by interaction with an Atoh1 3' enhancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Identification of stem cells in small intestine and colon by marker gene Lgr5

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Epidermal stem cells of the skin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Wnt signalling induces maturation of Paneth cells in intestinal crypts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Notch1 functions as a tumor suppressor in mouse skin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Intestinal label-retaining cells are secretory precursors expressing Lgr5.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

R-Spondin proteins: a novel link to beta-catenin activation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Expression pattern of Wnt signaling components in the adult intestine.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394041

Notch signals control the fate of immature progenitor cells in the intestine

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25818302

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cellular inheritance of a Cre-activated reporter gene to determine Paneth cell longevity in the murine small intestine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25818302

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELREP.2015.03.007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25818302%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25818302%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25818302%20AND%20SRC:MED&resulttype=core&format=json