Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1 (Q35415906)

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English	Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1	scientific article

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scholarly article

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9 February 2020

Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1 (English)

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9 February 2020

Kanokkarn Phromnoi

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9 February 2020

Pornngarm Limtrakul

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9 February 2020

Pornngarm Limtrakul

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9 February 2020

author name string

Sahdeo Prasad

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9 February 2020

Subash C Gupta

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9 February 2020

Ramaswamy Kannappan

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9 February 2020

Simone Reuter

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9 February 2020

Bharat B Aggarwal

8

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9 February 2020

publication date

4 August 2011

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9 February 2020

Molecular Pharmacology

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9 February 2020

80

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9 February 2020

5

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9 February 2020

889-899

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9 February 2020

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors.

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27 July 2018

A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents.

1 reference

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Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3

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Boswellic acid blocks signal transducers and activators of transcription 3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase SHP-1.

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Butein suppresses constitutive and inducible signal transducer and activator of transcription (STAT) 3 activation and STAT3-regulated gene products through the induction of a protein tyrosine phosphatase SHP-1.

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Reversal of P-glycoprotein-mediated multidrug resistance by 5,6,7,3',4'-pentamethoxyflavone (Sinensetin).

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10.1124/MOL.111.073676

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9 February 2020

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9 February 2020

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9 February 2020

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