Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis (Q35529234)

8 August 2017

Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis (English)

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8 August 2017

Plasmodium falciparum

0 references

author

Thomas D Otto

4

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8 August 2017

6

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PubMed ID

25521112

8 August 2017

Dominic P. Kwiatkowski

7

1 reference

8 August 2017

William L Hamilton

2

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Antoine Claessens

object named as

Antoine Claessens

1

0 references

Mihir Kekre

3

object named as

Mihir Kekre

1 reference

8 August 2017

Adnan Faizullabhoy

5

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8 August 2017

18 December 2014

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8 August 2017

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8 August 2017

10

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8 August 2017

e1004812

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8 August 2017

12

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Creative Commons Attribution 4.0 International

8 August 2017

start time

18 December 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families

1 reference

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A network approach to analyzing highly recombinant malaria parasite genes

12 July 2018

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Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity

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The antigenic switching network of Plasmodium falciparum and its implications for the immuno-epidemiology of malaria

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Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytes

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Hypervariable antigen genes in malaria have ancient roots

12 July 2018

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Asexual populations of the human malaria parasite, Plasmodium falciparum, use a two-step genomic strategy to acquire accurate, beneficial DNA amplifications

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1 reference

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Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families

12 July 2018

1 reference

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1 reference

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1 reference

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1 reference

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A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Evolution of the multi-domain structures of virulence genes in the human malaria parasite, Plasmodium falciparum

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Antigenic variation and the generation of diversity in malaria parasites

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Global malaria mortality between 1980 and 2010: a systematic analysis

12 July 2018

1 reference

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Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

LookSeq: A browser-based viewer for deep sequencing data

12 July 2018

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The Sequence Alignment/Map format and SAMtools

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Ectopic recombination of a malaria var gene during mitosis associated with an altered var switch rate.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Adaptive copy number evolution in malaria parasites

12 July 2018

1 reference

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Antigenic variation in Plasmodium falciparum

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Erythrocyte binding protein PfRH5 polymorphisms determine species-specific pathways of Plasmodium falciparum invasion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Plasmodium falciparum antigenic variation. Mapping mosaic var gene sequences onto a network of shared, highly polymorphic sequence blocks

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Frequent recombination events generate diversity within the multi-copy variant antigen gene families of Plasmodium falciparum

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Finding a match: how do homologous sequences get together for recombination?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Gene conversion: mechanisms, evolution and human disease

12 July 2018

1 reference

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An approach to classifying sequence tags sampled from Plasmodium falciparum var genes

12 July 2018

1 reference

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Global genetic diversity and evolution of var genes associated with placental and severe childhood malaria

12 July 2018

1 reference

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Genome sequence of the human malaria parasite Plasmodium falciparum

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Classification of adhesive domains in the Plasmodium falciparum erythrocyte membrane protein 1 family

12 July 2018

1 reference

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Genetic analysis of the human malaria parasite plasmodium falciparum

12 July 2018

1 reference

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Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross

12 July 2018

1 reference

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Cultivation of malarial parasites

12 July 2018

1 reference

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Quantitative dissection of clone-specific growth rates in cultured malaria parasites

12 July 2018

1 reference

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Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites.

26 September 2018

1 reference

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Evidence that Plasmodium falciparum chromosome end clusters are cross-linked by protein and are the sites of both virulence gene silencing and activation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Var gene diversity in Plasmodium falciparum is generated by frequent recombination events.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

Intra-cluster recombination and var transcription switches in the antigenic variation of Plasmodium falciparum.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270465

10.1371/JOURNAL.PGEN.1004812

26 September 2018

Identifiers

DOI

1 reference

8 August 2017

1 reference

8 August 2017

1 reference

PubMed ID

25521112