β-hydroxybutyrate: much more than a metabolite (Q35553084)

8 August 2017

1 reference

title

β-hydroxybutyrate: much more than a metabolite (English)

1 reference

8 August 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25193333%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

John C Newman

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25193333%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

19 August 2014

1 reference

25193333

Diabetes Research and Clinical Practice

8 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25193333%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25193333%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25193333%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

173-181

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25193333%20AND%20SRC:MED&resulttype=core&format=json

NAD+ and sirtuins in aging and disease

1 June 2020

cites work

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12 July 2018

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β-Hydroxybutyrate modulates N-type calcium channels in rat sympathetic neurons by acting as an agonist for the G-protein-coupled receptor FFA3.

12 July 2018

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12 July 2018

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12 July 2018

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Three single nucleotide variants of the HDAC gene are associated with type 2 diabetes mellitus in a Chinese population: a community-based case-control study

12 July 2018

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12 July 2018

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Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

12 July 2018

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Treatment of Diabetes and Diabetic Complications With a Ketogenic Diet

12 July 2018

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12 July 2018

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Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

12 July 2018

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Glucagon-induced acetylation of Foxa2 regulates hepatic lipid metabolism

12 July 2018

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12 July 2018

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Histone acetylation: molecular mnemonics on the chromatin.

12 July 2018

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A ketogenic diet increases brown adipose tissue mitochondrial proteins and UCP1 levels in mice

12 July 2018

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Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor

12 July 2018

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Short chain fatty acids and their receptors: new metabolic targets

12 July 2018

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HDAC inhibitor-based therapies: can we interpret the code?

12 July 2018

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Influence of threonine metabolism on S-adenosylmethionine and histone methylation

12 July 2018

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Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue

12 July 2018

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Metabolic reprogramming by class I and II histone deacetylases

12 July 2018

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Mitochondrial sirtuins: regulators of protein acylation and metabolism

12 July 2018

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The dynamic regulation of NAD metabolism in mitochondria

12 July 2018

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G protein-coupled receptors for energy metabolites as new therapeutic targets

12 July 2018

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Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

12 July 2018

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Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility

12 July 2018

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Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.

12 July 2018

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Low-carbohydrate diets: a matter of love or hate

12 July 2018

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Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

12 July 2018

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SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

12 July 2018

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Reversal of diabetic nephropathy by a ketogenic diet.

12 July 2018

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Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)

12 July 2018

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Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism

12 July 2018

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Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet.

12 July 2018

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12 July 2018

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The ketogenic diet inhibits the mammalian target of rapamycin (mTOR) pathway

12 July 2018

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Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells

12 July 2018

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Obesity, insulin resistance and free fatty acids

12 July 2018

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mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

12 July 2018

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mTORC1 controls fasting-induced ketogenesis and its modulation by ageing.

12 July 2018

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SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production

12 July 2018

1 reference

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Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability

12 July 2018

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Oxidative Stress and Diabetic Complications

12 July 2018

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A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414487

Insulin sensitivity and glucose tolerance are altered by maintenance on a ketogenic diet.

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Neuroprotection in diet-induced ketotic rat brain after focal ischemia

12 July 2018

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Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

12 July 2018

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12 July 2018

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Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis

12 July 2018

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Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

12 July 2018

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12 July 2018

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12 July 2018

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Acetylation and deacetylation of non-histone proteins

12 July 2018

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(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.

12 July 2018

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Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes.

12 July 2018

1 reference

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Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.

12 July 2018

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PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect

12 July 2018

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The retinoblastoma-histone deacetylase 3 complex inhibits PPARgamma and adipocyte differentiation

12 July 2018

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Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: a control enzyme in ketogenesis

12 July 2018

1 reference

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Physiological roles of ketone bodies as substrates and signals in mammalian tissues

12 July 2018

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12 July 2018

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Treatment of rats with glucagon or mannoheptulose increases mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase activity and decreases succinyl-CoA content in liver

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414487

Glucagon activates mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in vivo by decreasing the extent of succinylation of the enzyme

12 July 2018

1 reference

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GSK256073, a selective agonist of G-protein coupled receptor 109A (GPR109A) reduces serum glucose in subjects with type 2 diabetes mellitus.

12 July 2018

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Response of C57Bl/6 mice to a carbohydrate-free diet

26 September 2018

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Connecting threads: epigenetics and metabolism

26 September 2018

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Treatment with beta-hydroxybutyrate and melatonin is associated with improved survival in a porcine model of hemorrhagic shock

26 September 2018

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Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis

26 September 2018

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Small-volume d-β-hydroxybutyrate solution infusion increases survivability of lethal hemorrhagic shock in rats

26 September 2018

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Chronic in vitro ketosis is neuroprotective but not anti-convulsant.

26 September 2018

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Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation

26 September 2018

1 reference

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The ketogenic diet and epilepsy

26 September 2018

1 reference

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Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice.

26 September 2018

1 reference

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Sodium butyrate prevents lethality of severe sepsis in rats

26 September 2018

1 reference

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D-beta-hydroxybutyrate is neuroprotective against hypoxia in serum-free hippocampal primary cultures

26 September 2018

1 reference

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Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

26 September 2018

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dl-3-Hydroxybutyrate administration prevents myocardial damage after coronary occlusion in rat hearts

26 September 2018

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Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet

26 September 2018

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Ketogenic diet prevents cardiac arrest-induced cerebral ischemic neurodegeneration

26 September 2018

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12 December 2020

The reduced sensitivity to insulin of rats and mice fed on a carbohydrate-free, excess-fat diet

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12 December 2020

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12 December 2020

A high-fat, ketogenic diet induces a unique metabolic state in mice

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12 December 2020

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25193333%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25193333%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

25193333

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25193333%20AND%20SRC:MED&resulttype=core&format=json