Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms. (Q35558846)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065781%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms (English)

1 reference

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16 January 2020

6

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16 January 2020

Urban Lendahl

9

1 reference

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16 January 2020

author name string

Sebastian K-J Landor

1

1 reference

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16 January 2020

Anders P Mutvei

2

1 reference

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16 January 2020

Veronika Mamaeva

3

1 reference

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16 January 2020

Shaobo Jin

4

1 reference

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16 January 2020

Morten Busk

5

1 reference

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16 January 2020

Tove J Grönroos

7

1 reference

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16 January 2020

Pauliina Kronqvist

8

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16 January 2020

Cecilia Maria Sahlgren

10

1 reference

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16 January 2020

language of work or name

English

0 references

publication date

7 November 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065781%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

16 January 2020

published in

1 reference

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16 January 2020

volume

108

1 reference

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16 January 2020

issue

46

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16 January 2020

page(s)

18814-18819

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065781%20AND%20SRC:MED&resulttype=core&format=json

Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

16 January 2020

cites work

1 reference

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Notch-1 activation-dependent p53 restoration contributes to resveratrol-induced apoptosis in glioblastoma cells

12 July 2018

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p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategies

12 July 2018

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Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells

12 July 2018

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Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma.

12 July 2018

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Trp53 regulates Notch 4 signaling through Mdm2.

12 July 2018

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12 July 2018

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Generating specificity and diversity in the transcriptional response to hypoxia

12 July 2018

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12 July 2018

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Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.

12 July 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

12 July 2018

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Notch signaling: the core pathway and its posttranslational regulation

12 July 2018

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The canonical Notch signaling pathway: unfolding the activation mechanism

12 July 2018

1 reference

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Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression

12 July 2018

1 reference

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Mitochondria: from bioenergetics to the metabolic regulation of carcinogenesis.

12 July 2018

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Mitochondria in cancer: not just innocent bystanders

12 July 2018

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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

12 July 2018

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Tumor metabolism: cancer cells give and take lactate

12 July 2018

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A functional Notch-survivin gene signature in basal breast cancer

12 July 2018

1 reference

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Rbpj conditional knockout reveals distinct functions of Notch4/Int3 in mammary gland development and tumorigenesis

12 July 2018

1 reference

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Rational targeting of Notch signaling in cancer

12 July 2018

1 reference

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Tumor cell metabolism: cancer's Achilles' heel

12 July 2018

1 reference

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Notch signaling mediates hypoxia-induced tumor cell migration and invasion

12 July 2018

1 reference

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Mitochondria in cancer cells: what is so special about them?

12 July 2018

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Hypoxia-inducible factor 1 (HIF-1) pathway

12 July 2018

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HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation

12 July 2018

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AKT/PKB signaling: navigating downstream

12 July 2018

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A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

12 July 2018

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Hypoxia-inducible factors: central regulators of the tumor phenotype

12 July 2018

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

12 July 2018

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Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

12 July 2018

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p53 regulates mitochondrial respiration

12 July 2018

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Aberrant activation of notch signaling in human breast cancer

12 July 2018

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Hypoxia requires notch signaling to maintain the undifferentiated cell state

12 July 2018

1 reference

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Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

12 July 2018

1 reference

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Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements

12 July 2018

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Why do cancers have high aerobic glycolysis?

12 July 2018

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

12 July 2018

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Notch signaling in mammary development and oncogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219154

Notch in mammary gland development and breast cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219154

Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells

12 July 2018

1 reference

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The role of Notch in tumorigenesis: oncogene or tumour suppressor?

12 July 2018

1 reference

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Notch signaling in mammary gland tumorigenesis

12 July 2018

1 reference

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Oncogenic alterations of metabolism

12 July 2018

1 reference

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The role of p53 in glucose metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219154

Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219154

Activated Notch1 interacts with p53 to inhibit its phosphorylation and transactivation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219154

A novel NOTCH3 frameshift deletion and mitochondrial abnormalities in a patient with CADASIL.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219154

Mitochondrial impairment in p53-deficient human cancer cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219154

Mitochondrial dysfunction associated with a mutation in the Notch3 gene in a CADASIL family.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219154

The Allen Brain Atlas: 5 years and beyond

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1104943108

Crosstalk of Notch with p53 and p63 in cancer growth control

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22065781

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1104943108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065781%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065781%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference